Anti-OAS3 antibody (ab188111)
Key features and details
- Goat polyclonal to OAS3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-OAS3 antibody
See all OAS3 primary antibodies -
Description
Goat polyclonal to OAS3 -
Host species
Goat -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human OAS3 aa 350-450 (internal sequence) (Cysteine residue).
Database link: Q9Y6K5 -
Positive control
- A431 cell line lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.24% Tris, 0.87% Sodium chloride, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab188111 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab188111 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 121 kDa).
1 hour primary incubation is recommended for this product. |
Notes |
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WB
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 121 kDa). 1 hour primary incubation is recommended for this product. |
Target
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Function
May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. -
Tissue specificity
Present at high level in placenta trophoblast. -
Sequence similarities
Belongs to the 2-5A synthase family. - Information by UniProt
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Database links
- Entrez Gene: 4940 Human
- Omim: 603351 Human
- SwissProt: Q9Y6K5 Human
- Unigene: 528634 Human
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Alternative names
- (2-5'')oligo(A) synthase 3 antibody
- 2 5' oligo(A) synthetase 3 antibody
- 2 5'LIGO antibody
see all
Images
Datasheets and documents
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Datasheet download
References (1)
ab188111 has been referenced in 1 publication.
- Goonawardane N et al. Association of Zinc Finger Antiviral Protein Binding to Viral Genomic RNA with Attenuation of Replication of Echovirus 7. mSphere 6:N/A (2021). PubMed: 33408233