Overview

  • Product name
  • Description
    Rabbit polyclonal to OASL
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 231-470 of Human OASL (Uniprot ID Q15646).

  • Positive control
    • U87-MG whole cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab155422 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 59 kDa.

Target

  • Function
    Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
  • Tissue specificity
    Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
  • Sequence similarities
    Belongs to the 2-5A synthase family.
    Contains 2 ubiquitin-like domains.
  • Domain
    The ubiquitin-like domains are essential for its antiviral activity.
  • Cellular localization
    Cytoplasm and Nucleus > nucleolus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2' 5' oligoadenylate synthetase like antibody
    • 2''-5''-OAS-related protein antibody
    • 2''-5''-OAS-RP antibody
    • 2''-5''-oligoadenylate synthase-like protein antibody
    • 2'-5' oligoadenylate synthetase-like 2 antibody
    • 2'-5'-oligoadenylate synthetase-like antibody
    • 59 kDa 2' 5' oligoadenylate synthetase like protein antibody
    • 59 kDa 2''-5''-oligoadenylate synthase-like protein antibody
    • 59 kDa 2'-5'-oligoadenylate synthetase-like protein antibody
    • M1204 antibody
    • Mmu-OASL antibody
    • OASL antibody
    • OASL_HUMAN antibody
    • Oasl2 antibody
    • p59 OASL antibody
    • p59OASL antibody
    • THYROID HORMONE RECEPTOR INTERACTOR 14 antibody
    • Thyroid receptor interacting protein 14 antibody
    • Thyroid receptor-interacting protein 14 antibody
    • TR-interacting protein 14 antibody
    • TRIP-14 antibody
    • TRIP14 antibody
    see all

Images

  • Anti-OASL antibody (ab155422) at 1/1000 dilution + U87-MG whole cell lysate at 30 µg

    Predicted band size: 59 kDa



    7.5% SDS PAGE

References

ab155422 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab155422.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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