Overview

  • Product name
    Anti-OASL antibody - N-terminal
    See all OASL primary antibodies
  • Description
    Rabbit polyclonal to OASL - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ICC, ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human OASL. 17 amino acid peptide.
    Database link: Q15646

  • Positive control
    • HepG2 cells; mouse bladder tissue lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab191701 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use a concentration of 2.5 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 59 kDa.

Target

  • Function
    Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
  • Tissue specificity
    Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
  • Sequence similarities
    Belongs to the 2-5A synthase family.
    Contains 2 ubiquitin-like domains.
  • Domain
    The ubiquitin-like domains are essential for its antiviral activity.
  • Cellular localization
    Cytoplasm and Nucleus > nucleolus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2' 5' oligoadenylate synthetase like antibody
    • 2''-5''-OAS-related protein antibody
    • 2''-5''-OAS-RP antibody
    • 2''-5''-oligoadenylate synthase-like protein antibody
    • 2'-5' oligoadenylate synthetase-like 2 antibody
    • 2'-5'-oligoadenylate synthetase-like antibody
    • 59 kDa 2' 5' oligoadenylate synthetase like protein antibody
    • 59 kDa 2''-5''-oligoadenylate synthase-like protein antibody
    • 59 kDa 2'-5'-oligoadenylate synthetase-like protein antibody
    • M1204 antibody
    • Mmu-OASL antibody
    • OASL antibody
    • OASL_HUMAN antibody
    • Oasl2 antibody
    • p59 OASL antibody
    • p59OASL antibody
    • THYROID HORMONE RECEPTOR INTERACTOR 14 antibody
    • Thyroid receptor interacting protein 14 antibody
    • Thyroid receptor-interacting protein 14 antibody
    • TR-interacting protein 14 antibody
    • TRIP-14 antibody
    • TRIP14 antibody
    see all

Images

  • Anti-OASL antibody - N-terminal (ab191701) at 1 µg/ml + mouse bladder tissue lysate at 15 µg

    Predicted band size: 59 kDa

  • Immunofluorescent analysis of HepG2 cells labeling OASL using ab191701 at 20 μg/ml.

  • Immunocytochemical analysis of HepG2 cells labeling OASL using ab191701 at 2.5 μg/ml.

References

ab191701 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191701.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up