Overview

  • Product nameAnti-OATP2 antibody
    See all OATP2 primary antibodies
  • Description
    Rabbit polyclonal to OATP2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 273-302 of Human OATP2 (Q9Y6L6)

  • Positive control
    • HepG2 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab103065 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 76 kDa.

Target

  • FunctionMediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. May play an important role in the clearance of bile acids and organic anions from the liver.
  • Tissue specificityHighly expressed in liver. Not detected in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte.
  • Sequence similaritiesBelongs to the organo anion transporter (TC 2.A.60) family.
    Contains 1 Kazal-like domain.
  • Cellular localizationBasolateral cell membrane. Detected in basolateral membranes of hepatocytes.
  • Information by UniProt
  • Database links
  • Alternative names
    • Liver-specific organic anion transporter 1 antibody
    • LST-1 antibody
    • LST1 antibody
    • OATP-2 antibody
    • OATP-C antibody
    • OATP1B1 antibody
    • OATPC antibody
    • SLC21A6 antibody
    • SLCO1B1 antibody
    • SO1B1_HUMAN antibody
    • Sodium-independent organic anion-transporting polypeptide 2 antibody
    • Solute carrier family 21 member 6 antibody
    • Solute carrier organic anion transporter family member 1B1 antibody
    see all

Anti-OATP2 antibody images

  • Anti-OATP2 antibody (ab103065) at 1/100 dilution + HepG2 cell lysate at 35 µg

    Predicted band size : 76 kDa

References for Anti-OATP2 antibody (ab103065)

ab103065 has not yet been referenced specifically in any publications.

Product Wall

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I blasted the immunogen sequence for ab103065, to see what the level of homology would be with mouse and rat would be, and for both the level of homogly is below 70%. Therefore I would not feel confident in reco...

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I have looked into the data again that the customer has shared with us and it seems that the antibody is picking up a non-specific band when the UGT1A1 is expressed. I understand that your c...

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