Anti-OAZ1 antibody - N-terminal (ab85221)

Overview

• Product name
  Anti-OAZ1 antibody - N-terminal
  See all OAZ1 primary antibodies
• Description
  Rabbit polyclonal to OAZ1 - N-terminal
• Tested applications
  Suitable for: WB, Indirect ELISAmore details
• Species reactivity
  Reacts with: Mouse, Human
  
• Immunogen

  Synthetic peptide selected from the N terminal region of Human OAZ1, conjugated to KLH (NP_004143).

• Positive control
  • Mouse heart tissue lysate.

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage buffer
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• Purity
  Ammonium Sulphate Precipitation
• Purification notes
  ab85221 is prepared by Saturated Ammonium Sulphate (SAS) precipitation followed by dialysis against PBS.
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Signal Transduction
  • Metabolism
  • Amino Acids

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Amino acid metabolism

  • Metabolism
  • Types of disease
  • Cancer

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Applications

Target

• Function
  Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
• Sequence similarities
  Belongs to the ODC antizyme family.

• Target information above from: UniProt accession P54368 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 4946 Human
  • Entrez Gene: 18245 Mouse
  • Omim: 601579 Human
  • SwissProt: P54368 Human
  • SwissProt: P54369 Mouse
  • Unigene: 446427 Human
  • Unigene: 398119 Mouse
• Alternative names
  • Antizyme 1 antibody
  • Antizyme antibody
  • AZI antibody

  • MGC138338 antibody
  • OAZ 1 antibody
  • OAZ antibody
  • OAZ1 antibody
  • OAZ1_HUMAN antibody
  • ODC Az antibody
  • ODC-Az antibody
  • Ornithine decarboxylase antizyme 1 antibody
  • Ornithine decarboxylase antizyme antibody

  see all

Protocols

• Western blot protocols