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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: 0.09% Sodium Azide
Concentration information loading...
Purity Ammonium Sulphate Precipitation
Purification notes ab85221 is prepared by Saturated Ammonium Sulphate (SAS) precipitation followed by dialysis against PBS.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/1000. Predicted molecular weight: 25 kDa.
Function Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
Sequence similarities Belongs to the ODC antizyme family.
Information by UniProt
Antizyme 1 antibody
Anti-OAZ1 antibody - N-terminal images
Western blot - OAZ1 antibody - N-terminal (ab85221)
Anti-OAZ1 antibody - N-terminal (ab85221) at 1/1000 dilution + Mouse heart tissue lysate at 35 µg Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 25 kDa Observed band size : 28 kDa ( why is the actual band size different from the predicted?) Additional bands at : 16 kDa,40 kDa. We are unsure as to the identity of these extra bands.
Blocking/Dilution buffer: 5% NFDM/TBST.
References for Anti-OAZ1 antibody - N-terminal (ab85221)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"