Overview

  • Product name
    Anti-OAZ1 antibody - N-terminal
    See all OAZ1 primary antibodies
  • Description
    Rabbit polyclonal to OAZ1 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, Indirect ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide selected from the N terminal region of Human OAZ1, conjugated to KLH (NP_004143).

  • Positive control
    • Mouse heart tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85221 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/1000. Predicted molecular weight: 25 kDa.
Indirect ELISA 1/1000.

Target

  • Function
    Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
  • Sequence similarities
    Belongs to the ODC antizyme family.
  • Information by UniProt
  • Database links
    • Alternative names
      • Antizyme 1 antibody
      • Antizyme antibody
      • AZI antibody
      • MGC138338 antibody
      • OAZ 1 antibody
      • OAZ antibody
      • OAZ1 antibody
      • OAZ1_HUMAN antibody
      • ODC Az antibody
      • ODC-Az antibody
      • Ornithine decarboxylase antizyme 1 antibody
      • Ornithine decarboxylase antizyme antibody
      see all

    Images

    • Western blot - OAZ1 antibody - N-terminal (ab85221)
      Western blot - OAZ1 antibody - N-terminal (ab85221)
      Anti-OAZ1 antibody - N-terminal (ab85221) at 1/1000 dilution + Mouse heart tissue lysate at 35 µg

      Secondary
      Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution

      Predicted band size: 25 kDa
      Observed band size: 28 kDa (why is the actual band size different from the predicted?)
      Additional bands at: 16 kDa, 40 kDa. We are unsure as to the identity of these extra bands.



      Blocking/Dilution buffer: 5% NFDM/TBST.

    References

    ab85221 has not yet been referenced specifically in any publications.

    Publishing research using ab85221? Please let us know so that we can cite the reference in this datasheet.

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