Overview

  • Product nameAnti-OBFC1 antibody
    See all OBFC1 primary antibodies
  • Description
    Rabbit polyclonal to OBFC1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Horse, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 297-346 (DKDLHRKIHR IIQQDCQKPN HMEKGCHFLH ILACARLSIR PGLSEAVLQQ) of Human OBFC1 (NP_079204).

  • Positive control
    • Human fetal heart lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab125515 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionComponent of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
  • Sequence similaritiesBelongs to the STN1 family.
    Contains 1 OB DNA-binding domain.
  • Cellular localizationNucleus. Chromosome > telomere.
  • Information by UniProt
  • Database links
  • Alternative names
    • AAF 44 antibody
    • AAF44 antibody
    • Alpha accessory factor 44 antibody
    • bA541N10.2 antibody
    • CST complex subunit STN1 antibody
    • FLJ22559 antibody
    • Obfc1 antibody
    • Oligonucleotide/oligosaccharide binding fold containing 1 antibody
    • Oligonucleotide/oligosaccharide-binding fold-containing protein 1 antibody
    • OTTHUMP00000020417 antibody
    • OTTHUMP00000020418 antibody
    • Replication protein A 32 kDa subunit antibody
    • RP11-541N10.2 antibody
    • RPA 32 antibody
    • STN1 antibody
    • STN1_HUMAN antibody
    • Suppressor of cdc thirteen antibody
    • Suppressor of cdc thirteen homolog antibody
    see all

Anti-OBFC1 antibody images

  • Anti-OBFC1 antibody (ab125515) at 1 µg/ml + Human fetal heart lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG-HRP

    Predicted band size : 42 kDa

References for Anti-OBFC1 antibody (ab125515)

ab125515 has not yet been referenced specifically in any publications.

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