Overview

  • Product nameAnti-OBFC2B antibody
    See all OBFC2B primary antibodies
  • Description
    Rabbit polyclonal to OBFC2B
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan, Elephant
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 161 - 211 of Human OBFC2B (NP_076973.1)

  • Positive control
    • Human breast or colon carcinoma. Mouse squamous cell carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab87265 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • RelevanceSingle-stranded DNA (ssDNA)-binding proteins, such as OBFC2B, are ubiquitous and essential for a variety of DNA metabolic processes, including replication, recombination, and detection and repair of damage. OBFC2B plays an important role in DNA damage response. It influences diverse endpoints in the cellular DNA damage response, including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. It associates with DNA lesions, and enables the efficient activation of ATM and consequent phosphorylation of downstream proteins.
  • Cellular localizationNuclear. Localizes to nuclear foci following DNA damage.
  • Database links
  • Alternative names
    • 2610036N15Rik antibody
    • hSSB1 antibody
    • LP3587 antibody
    • MGC125161 antibody
    • MGC2731 antibody
    • MGC30353 antibody
    • Nabp2 antibody
    • Nucleic acid binding protein 2 antibody
    • Oligonucleotide/oligosaccharide binding fold containing 2B antibody
    • Oligonucleotide/oligosaccharide binding fold containing protein 2B antibody
    • RGD1308158 antibody
    • Sensor of single strand DNA complex subunit B1 antibody
    • Sensor of ssDNA subunit B1 antibody
    • Single stranded DNA binding protein 1 antibody
    • SOSS complex subunit B1 antibody
    • SSB1 antibody
    see all

Anti-OBFC2B antibody images

  • ab87265 at a 1/500 dilution staining OBFC2B in Human colon carcinoma tissue. DAB staining.
  • ab87265 at a 1/500 dilution staining OBFC2B in Human colon carcinoma tissue. DAB staining.
  • ab87265 at a 1/100 dilution staining OBFC2B in Mouse squamous cell carcinoma tissue. DAB staining.

References for Anti-OBFC2B antibody (ab87265)

ab87265 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"