Overview

  • Product nameAnti-OLFML3 antibody
    See all OLFML3 primary antibodies
  • Description
    Rabbit polyclonal to OLFML3
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-228 of Human OLFML3 (AAH09920).

  • Positive control
    • A549 and HCT116 whole cell lysates; cal27 xenograft tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab111712 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/300. Predicted molecular weight: 46 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. or Tris-EDTA buffer ( PH8.0)

Target

  • FunctionSecreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.
  • Tissue specificityAbundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer.
  • Sequence similaritiesBelongs to the OLFML3 family.
    Contains 1 olfactomedin-like domain.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • HNOEL-iso antibody
    • hOLF44 antibody
    • OLF44 antibody
    • Olfactomedin like 3 antibody
    • Olfactomedin-like protein 3 antibody
    • OLFL3_HUMAN antibody
    • OLFML3 antibody
    see all

Anti-OLFML3 antibody images

  • Anti-OLFML3 antibody (ab111712) at 1/3000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size : 46 kDa
  • ab111712 at 1/500 dilution staining OLFML3 in Formalin-fixed, paraffin-embedded cal27 xenograft tissue by Immunohistochemistry.

References for Anti-OLFML3 antibody (ab111712)

ab111712 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"