Anti-Oncostatin M antibody [17001.31] (ab10842)

Overview

  • Product nameAnti-Oncostatin M antibody [17001.31]
    See all Oncostatin M primary antibodies
  • Description
    Mouse monoclonal [17001.31] to Oncostatin M
  • Specificityab10842 shows < 10% cross-reactivity with recombinant human LIF, but does not cross-react with recombinant mouse OSM and recombinant human IL6.
  • Tested applicationsSuitable for: ELISA, WB, Neutralisingmore details
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse
  • Immunogen

    Recombinant full length protein (Human) expressed in E. coli.

  • Positive control
    • Tested with human TF-1 cell line.

Properties

Applications

Our Abpromise guarantee covers the use of ab10842 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
Neutralising
  • Application notesELISA: Use at a concentration of 0.5-1 µg/ml.
    Neut: ND50 = 0.1 - 5 µg/ml
    WB: Use at a concentration of 1-2 µg/ml. Predicted molecular weight: 22 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionGrowth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
    • Sequence similaritiesBelongs to the LIF/OSM family.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • MGC20461 antibody
      • ONCM_HUMAN antibody
      • Oncostatin M antibody
      • Oncostatin-M antibody
      • OSM antibody
      see all

    References for Anti-Oncostatin M antibody [17001.31] (ab10842)

    ab10842 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry regarding product ab10842. Unfortunately there is no information available to indicate that the epitope of this antibody has been mapped. The only information we have is that the immunising protein was recombinant human O...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"