Overview

  • Product name
    Anti-ORC1 antibody [7A7]
    See all ORC1 primary antibodies
  • Description
    Rat monoclonal [7A7] to ORC1
  • Tested applications
    Suitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human ORC1 protein.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.1% Sodium Azide.
    Constituents: PBS.
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    7A7
  • Myeloma
    x63-Ag8.653
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab22533 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 97 kDa.

Target

  • Function
    Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
  • Sequence similarities
    Belongs to the ORC1 family.
    Contains 1 BAH domain.
  • Developmental stage
    Expression is cell-cycle regulated, it starts to accumulate in mid-G1 phase, reaches a peak at the G1/S boundary, and decreases to a basal level in S phase (at protein level).
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • HSORC1 antibody
    • MmORC1 antibody
    • orc1 antibody
    • ORC1_HUMAN antibody
    • ORC1L antibody
    • Origin Recognition Complex 1 antibody
    • Origin recognition complex subunit 1 (yeast homolog) like antibody
    • Origin recognition complex subunit 1 antibody
    • Origin recognition complex subunit 1 homolog antibody
    • Origin recognition complex subunit 1 like (S. cerevisia antibody
    • Origin recognition complex subunit 1 like antibody
    • Origin recognition complex subunit 1 S. cerevisiae homolog like antibody
    • Origin recognition complex, subunit 1 like (yeast) antibody
    • PARC1 antibody
    • Replication control protein 1 antibody
    see all

References for Anti-ORC1 antibody [7A7] (ab22533)

ab22533 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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