Anti-ORC1 antibody (ab138102)
Key features and details
- Rabbit polyclonal to ORC1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ORC1 antibody
See all ORC1 primary antibodies -
Description
Rabbit polyclonal to ORC1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide derived from an internal region of Human ORC1.
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Positive control
- HepG2 cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS is without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab138102 was affinity-purified from rabbit antiserum by immunogenic peptide affinity-chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab138102 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 97 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 97 kDa. |
Target
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Function
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. -
Sequence similarities
Belongs to the ORC1 family.
Contains 1 BAH domain. -
Developmental stage
Expression is cell-cycle regulated, it starts to accumulate in mid-G1 phase, reaches a peak at the G1/S boundary, and decreases to a basal level in S phase (at protein level). -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 4998 Human
- Omim: 601902 Human
- SwissProt: Q13415 Human
- Unigene: 17908 Human
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Alternative names
- HSORC1 antibody
- MmORC1 antibody
- orc1 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab138102 has not yet been referenced specifically in any publications.