Overview

  • Product name
    Anti-ORC3L antibody - C-terminal
    See all ORC3L primary antibodies
  • Description
    Rabbit polyclonal to ORC3L - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow, Xenopus laevis, Zebrafish, Xenopus tropicalis
  • Immunogen

    Synthetic peptide, corresponding to a region within C terminal amino acids 648-711 of Human ORC3L (Uniprot ID Q9UBD5).

  • Positive control
    • H1299 whole cell lysate; HeLa, HepG2 and A431 cell lines.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab153945 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 82 kDa.

Target

  • Function
    Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
  • Sequence similarities
    Belongs to the ORC3 family.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Homolog of Latheo antibody
    • homolog of latheo, Drosophila antibody
    • LAT antibody
    • LATHEO antibody
    • LATHEO, drosophila, homolog of antibody
    • orc3 antibody
    • ORC3_HUMAN antibody
    • ORC3L antibody
    • Origin recognition complex subunit 3 antibody
    • Origin recognition complex subunit 3 honolog antibody
    • Origin Recognition Complex Subunit 3 Isoform 1 antibody
    • Origin recognition complex subunit 3 like antibody
    • Origin recognition complex subunit Latheo antibody
    • Origin Recognition Complex, subunit 3, S. cerevisiae, homolog of antibody
    • Origin recognition complex, subunit 3-like (S. cerevisiae) antibody
    • Origin recognition complex, subunit 3-like (yeast) antibody
    see all

Images

  • Anti-ORC3L antibody - C-terminal (ab153945) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size: 82 kDa



    7.5% SDS PAGE

References

ab153945 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab153945.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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