Overview

  • Product name
    Anti-Orexin Prepro antibody
  • Description
    Rabbit polyclonal to Orexin Prepro
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Synthetic peptide 17aa (Mouse) (C terminal).

Properties

Applications

Our Abpromise guarantee covers the use of ab16584 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000 - 1/10000.
WB 1/1000. Predicted molecular weight: 14 kDa.

Target

  • Relevance
    Prepro-orexin is 130 amino acid long peptide with a putative 33 AA secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis. These neuropeptides bind and activate two closely related Orexin receptors—G-protein coupled receptors (GPCRs) OX1R and OX2R. Orexins (Orexin A and Orexin B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus. Orexin A and Orexin B are derived from the same precursor (Prepro-orexin) by proteolytic cleavage.
  • Cellular localization
    Cytoplasmic and Endoplasmic reticulum
  • Database links
  • Alternative names
    • HCRT antibody
    • Hypocretin antibody
    • OX antibody
    • PPORX antibody
    • PPOX antibody
    • Prepro orexin antibody
    see all

References

This product has been referenced in:
  • Mo Q  et al. Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus. J Steroid Biochem Mol Biol 114:135-43 (2009). Read more (PubMed: 19429443) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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