Overview

  • Product name
    Org 27569
  • Description
    Potent CB1 receptor allosteric modulator
  • Biological description
    Potent CB1 receptor allosteric modulator (pEC50 = 8.24). Significantly increases binding of the CB1 agonist [3H]CP 55,940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A (pKb = 5.95). Behaves as an insurmountable antagonist of receptor function in in vitro assays.
  • Purity
    > 99%

Properties

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