Anti-ornithine aminotransferase antibody (ab85186)

Overview

  • Product nameAnti-ornithine aminotransferase antibody
    See all ornithine aminotransferase primary antibodies
  • Description
    Rabbit polyclonal to ornithine aminotransferase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • Immunogen

    Synthetic peptide within residues: RTLSAISSST DPTSYDGFGP FMPGFDIIPY NDLPALERAL QDPNVAAFMV, corresponding to internal sequence amino acids 180-229 of Human ornithine aminotransferase (NP_000265)

  • Positive control
    • 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85186 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceOrnithine aminotransferase (OAT) is a key mitochondrial enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. OAT has also been linked with prostate cancer and alternatively activated macrophages
  • Cellular localizationMitochondrion matrix.
  • Database links
  • Alternative names
    • GACR antibody
    • Gyrate atrophy antibody
    • HOGA antibody
    • OAT antibody
    • OATASE antibody
    • OKT antibody
    • Ornithine aminotransferase (gyrate atrophy) antibody
    • Ornithine aminotransferase mitochondrial antibody
    • ornithine aminotransferase precursor antibody
    • Ornithine aminotransferase, mitochondrial precursor antibody
    • Ornithine delta aminotransferase antibody
    • Ornithine oxo acid aminotransferase antibody
    see all

Anti-ornithine aminotransferase antibody images

  • Anti-ornithine aminotransferase antibody (ab85186) at 1 µg/ml + 293T cell lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 45 kDa
    Observed band size : 45 kDa

References for Anti-ornithine aminotransferase antibody (ab85186)

ab85186 has not yet been referenced specifically in any publications.

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