Anti-Ornithine Decarboxylase/ODC antibody (ab97395)
Key features and details
- Rabbit polyclonal to Ornithine Decarboxylase/ODC
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Ornithine Decarboxylase/ODC antibody
See all Ornithine Decarboxylase/ODC primary antibodies -
Description
Rabbit polyclonal to Ornithine Decarboxylase/ODC -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human
Predicted to work with: Cow, Pig -
Immunogen
Recombinant fragment corresponding to Human Ornithine Decarboxylase/ODC aa 180-433.
Database link: P11926 -
Positive control
- WB: HepG2 cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab97395 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/100 - 1/1000.
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WB |
1/1000. Predicted molecular weight: 51 kDa.
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Notes |
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IHC-P
1/100 - 1/1000. |
WB
1/1000. Predicted molecular weight: 51 kDa. |
Target
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Pathway
Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1. -
Sequence similarities
Belongs to the Orn/Lys/Arg decarboxylase class-II family. -
Post-translational
modificationsS-Nitrosylation inhibits the enzyme. S-Nitrosylated in vitro on 4 cysteine residues. - Information by UniProt
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Database links
- Entrez Gene: 281365 Cow
- Entrez Gene: 4953 Human
- Entrez Gene: 18263 Mouse
- Entrez Gene: 414408 Pig
- Entrez Gene: 24609 Rat
- Omim: 165640 Human
- SwissProt: P27117 Cow
- SwissProt: P11926 Human
see all -
Alternative names
- DCOR_HUMAN antibody
- Dodc1 antibody
- Odc 1 antibody
see all
Images
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All lanes : Anti-Ornithine Decarboxylase/ODC antibody (ab97395) at 1/1000 dilution
Lane 1 : HepG2 whole cell lysate
Lane 2 : T47D whole cell lysate
Lysates/proteins at 30 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG antibody (HRP)
Predicted band size: 51 kDaThe signal was developed with Trident ECL plus-Enhanced.
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Paraffin embedded rat adrenal gland tissue stained for ODC using ab97395 at 1/500 dilution in immunohistochemical analysis.
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Paraffin embedded mouse heart tissue stained for ODC using ab97395 at 1/1000 dilution in immunohistochemical analysis.
Datasheets and documents
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SDS download
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Datasheet download
References (14)
ab97395 has been referenced in 14 publications.
- Park MG et al. DMSO-tolerant ornithine decarboxylase (ODC) tandem assay optimised for high-throughput screening. J Enzyme Inhib Med Chem 38:309-318 (2023). PubMed: 36451618
- Urban-Wójciuk Z et al. The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme. Cancer Gene Ther 29:940-950 (2022). PubMed: 34522028
- Zhao L et al. mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A. Cell Biosci 12:183 (2022). PubMed: 36371321
- Zhang X et al. Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway. Int J Mol Med 47:N/A (2021). PubMed: 33537831
- Halloran KM et al. Pre-implantation exogenous progesterone and pregnancy in sheep. II. Effects on fetal-placental development and nutrient transporters in late pregnancy. J Anim Sci Biotechnol 12:46 (2021). PubMed: 33827696