Overview

  • Product nameAnti-ORP8 antibody
    See all ORP8 primary antibodies
  • Description
    Rabbit polyclonal to ORP8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (

    SQRQGKEAYPTPTKDLHQPSLSPASPHSQGFERGKEDISQNKDESSLSMS

    ) of Human OSBPL8 (NP_001003712)

  • Positive control
    • 721_B cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab84178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 101 kDa (predicted molecular weight: 101 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceORP8 is a member of the oxysterol-binding protein related protein family. In humans, the gene family consists of 12 members, and extensive splice variation increases the number of encoded protein products substantially. The ORPs have been implicated as sterol sensors that regulate a number of cellular functions including sterol and neutral lipid metabolism, intracellular lipid transport, membrane trafficking and cell signaling. ORP8 has been recently shown to act as a sterol sensor that affects the reverse cholesterol transport process via modulation of ABCA1 expression and macrophage cholesterol efflux.
  • Cellular localizationEndoplasmic reticulum
  • Database links
  • Alternative names
    • DKFZp686A11164 antibody
    • KIAA1451 antibody
    • MGC126578 antibody
    • MGC133203 antibody
    • MST120 antibody
    • MSTP120 antibody
    • ORP 8 antibody
    • OSBP related protein 8 antibody
    • OSBP10 antibody
    • OSBPL8 antibody
    • Oxysterol binding protein like 8 antibody
    • Oxysterol binding protein like protein 8 antibody
    • Oxysterol binding protein related protein 8 antibody
    see all

Anti-ORP8 antibody images

  • Anti-ORP8 antibody (ab84178) at 1 µg/ml + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 101 kDa
    Observed band size : 101 kDa
    Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.

References for Anti-ORP8 antibody (ab84178)

ab84178 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"