Anti-Osteocalcin antibody [4C2] (HRP) (ab32602)

Overview

• Product nameAnti-Osteocalcin antibody [4C2] (HRP)
  See all Osteocalcin primary antibodies
• Description
  Mouse monoclonal [4C2] to Osteocalcin (HRP)
• ConjugationHRP
• SpecificityAb32602 recognises that N-terminal domain of Osteocalcin.
• Tested applicationsSuitable for: ELISAmore details
• Species reactivity
  Reacts with: Rat
  Does not react with: Human
• Immunogen

  Synthetic peptide corresponding to Rat Osteocalcin.
  Database link: P04640

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at +4°C.
• Storage bufferPreservative: 0.1% Proclin
  Constituents: 1% BSA, PBS, pH 7.4
• Concentration information loading...
• PurityProtein A purified
• ClonalityMonoclonal
• Clone number4C2
• IsotypeIgG1
• Light chain typekappa
• Research areas
  • Signal Transduction
  • Cytoskeleton / ECM
  • Extracellular Matrix
  • Structures
  • Bone

  • Stem Cells
  • Mesenchymal Stem Cells
  • Osteogenesis

Associated products

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)
• Related Products
  • TMB ELISA Substrate (Highest Sensitivity) (ab171522)
  • TMB ELISA Substrate (High Sensitivity) (ab171523)
  • TMB ELISA Substrate (Fast Kinetic Rate) (ab171524)
  • TMB ELISA Substrate (Slow Kinetic Rate) (ab171525)
  • TMB ELISA Substrate (Slower Kinetic Rate) (ab171526)
  • TMB ELISA Substrate (Slowest Kinetic Rate) (ab171527)
  • 450 nm Stop Solution for TMB Substrate (ab171529)
  • 650 nm Stop Solution for TMB Substrate (ab171531)
  • Immunoassay Blocking Buffer (ab171534)
  • Immunoassay Blocking (BSA Free) (ab171535)

Applications

Target

• FunctionConstitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
• Sequence similaritiesBelongs to the osteocalcin/matrix Gla protein family.
  Contains 1 Gla (gamma-carboxy-glutamate) domain.
• Post-translational
  modificationsGamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
• Cellular localizationSecreted.

• Target information above from: UniProt accession P02818 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 25295 Rat
  • SwissProt: P04640 Rat
  • Unigene: 9722 Rat
• Alternative names
  • BGLAP antibody
  • BGP antibody
  • Bone gamma carboxyglutamate (gla) protein antibody

  • Bone gamma carboxyglutamate gla protein osteocalcin antibody
  • Bone gamma carboxyglutamate protein antibody
  • Bone Gla protein antibody
  • Gamma carboxyglutamic acid containing protein antibody
  • Gamma-carboxyglutamic acid-containing protein antibody
  • OC antibody
  • OCN antibody
  • OSTCN_HUMAN antibody
  • Osteocalcin antibody
  • OTTHUMP00000016586 antibody
  • PMF1 antibody

  see all