Anti-Osteocalcin antibody [5D1] (ab22433)

Overview

  • Product nameAnti-Osteocalcin antibody [5D1]
    See all Osteocalcin primary antibodies
  • Description
    Mouse monoclonal [5D1] to Osteocalcin
  • Specificityab22433 recognises specifically C terminal domain of osteocalcin.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Rat
    Does not react with: Human
  • Immunogen

    Synthetic peptide (Rat) conjugated to BSA (C terminal).

  • EpitopeC terminal domain of Osteocalcin.

Properties

Applications

Our Abpromise guarantee covers the use of ab22433 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 10 µg/ml. (plate coating)

Target

  • FunctionConstitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
  • Sequence similaritiesBelongs to the osteocalcin/matrix Gla protein family.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.
  • Post-translational
    modifications
    Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • BGLAP antibody
    • BGP antibody
    • Bone gamma carboxyglutamate (gla) protein antibody
    • Bone gamma carboxyglutamate gla protein osteocalcin antibody
    • Bone gamma carboxyglutamate protein antibody
    • Bone Gla protein antibody
    • Gamma carboxyglutamic acid containing protein antibody
    • Gamma-carboxyglutamic acid-containing protein antibody
    • OC antibody
    • OCN antibody
    • OSTCN_HUMAN antibody
    • Osteocalcin antibody
    • OTTHUMP00000016586 antibody
    • PMF1 antibody
    see all

Anti-Osteocalcin antibody [5D1] images

  • Osteocalcin ELISA standard curve obtained using increasing concentrations of osteocalcin and 10 ug/ml ab22433 for coating the ELISA plates.

References for Anti-Osteocalcin antibody [5D1] (ab22433)

ab22433 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your email. The originator of ab22433 tested the antibody in ELISA as follows and with a peroxidase-conjugated monoclonal antibody [4C2] to rat BGP N-terminal. We currently do not carry this antibody, but I can see if it can be added to o...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"