Overview

  • Product nameAnti-Osteopontin antibody
    See all Osteopontin primary antibodies
  • Description
    Rabbit polyclonal to Osteopontin
  • SpecificityThere were no cross reactivities obtained with human Osteonectin, and human Bone Sialoprotein.
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    PSKSNESHDHMDDMDD

    , corresponding to amino acids 59-74 of Human Osteopontin

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab14175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration.
ELISA 1/1000.
IHC-P 1/1500.

Target

  • FunctionBinds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.
    Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
  • Tissue specificityBone. Found in plasma.
  • Sequence similaritiesBelongs to the osteopontin family.
  • Post-translational
    modifications
    Extensively phosphorylated on clustered serine residues.
    N- and O-glycosylated.
    Phosphorylation sites are present in the extracelllular medium.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • BNSP antibody
    • Bone sialoprotein 1 antibody
    • BSP I antibody
    • BSPI antibody
    • Early T lymphocyte activation 1 antibody
    • ETA 1 antibody
    • ETA1 antibody
    • MGC110940 antibody
    • Nephropontin antibody
    • OPN antibody
    • Osteopontin antibody
    • osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein antibody
    • OSTP_HUMAN antibody
    • PSEC0156 antibody
    • secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) antibody
    • Secreted phosphoprotein 1 antibody
    • SPP 1 antibody
    • SPP-1 antibody
    • SPP1 antibody
    • SPP1/CALPHA1 fusion antibody
    • Urinary stone protein antibody
    • Uropontin antibody
    see all

References for Anti-Osteopontin antibody (ab14175)

This product has been referenced in:
  • Poole DH  et al. Expression and regulation of secreted phosphoprotein 1 in the bovine corpus luteum and effects on T lymphocyte chemotaxis. Reproduction 146:527-37 (2013). WB . Read more (PubMed: 24019509) »
  • Lavoie JF  et al. Skin-derived precursors differentiate into skeletogenic cell types and contribute to bone repair. Stem Cells Dev 18:893-906 (2009). Read more (PubMed: 18834279) »

See all 2 Publications for this product

Product Wall

Thank you for your enquiry and your patience. I apologize for the delay in responding to you. I was awaiting confirmation of the information. ab27710 and ab27711 have been paired together in an ELISA. We recommend using ab27710 as the coating ant...

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