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ab8448 has been referenced in 83 publications.
He W et al.Effects of silica-gentamicin nanohybrids on osteogenic differentiation of human osteoblast-like SaOS-2 cells.Int J Nanomedicine 13:877-893 (2018).
PubMed: 29445277
Dickerson MT et al.Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic ß-cells.PLoS One 12:e0175069 (2017).
ICC/IF
;
Mouse
.
PubMed: 28403169
Corciulo C et al.Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression.Nat Commun 8:15019 (2017).
Mouse, Rat
.
PubMed: 28492224
Luo G et al.Icariside II promotes the osteogenic differentiation of canine bone marrow mesenchymal stem cells via the PI3K/AKT/mTOR/S6K1 signaling pathways.Am J Transl Res 9:2077-2087 (2017).
PubMed: 28559962
Lee SH et al.Effect of Rosuvastatin on Bovine Pericardial Aortic Tissue Valve Calcification in a Rat Subdermal Implantation Model.Korean Circ J 47:401-408 (2017).
PubMed: 28567091
Li T et al.Sulodexide recovers endothelial function through reconstructing glycocalyx in the balloon-injury rat carotid artery model.Oncotarget 8:91350-91361 (2017).
IHC-P
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Rat
.
PubMed: 29207649
Xu C et al.Osteopontin is involved in TLR4 pathway contributing to ovarian cancer cell proliferation and metastasis.Oncotarget 8:98394-98404 (2017).
PubMed: 29228698
Sun HF et al.Delisheng induces antiproliferation and apoptosis effects in Hep3B cells via modulation of angiogenic proteins.Oncol Lett 14:6578-6584 (2017).
PubMed: 29163690
Joshi S et al.Transcriptional study of hyperoxaluria and calcium oxalate nephrolithiasis in male rats: Inflammatory changes are mainly associated with crystal deposition.PLoS One 12:e0185009 (2017).
PubMed: 29091707
Wang M et al.Radiation Resistance in KRAS-Mutated Lung Cancer Is Enabled by Stem-like Properties Mediated by an Osteopontin-EGFR Pathway.Cancer Res 77:2018-2028 (2017).
PubMed: 28202526
Cao J et al.Rapamycin inhibits CaCl2-induced thoracic aortic aneurysm formation in rats through mTOR-mediated suppression of proinflammatory mediators.Mol Med Rep 16:1911-1919 (2017).
PubMed: 28656223
Chen S et al.Designer D-form self-assembling peptide scaffolds promote the proliferation and migration of rat bone marrow-derived mesenchymal stem cells.Int J Mol Med 40:679-688 (2017).
PubMed: 28677805
Nagaraju CK et al.Global fibroblast activation throughout the left ventricle but localized fibrosis after myocardial infarction.Sci Rep 7:10801 (2017).
PubMed: 28883544
Saleh S et al.Osteopontin regulates proliferation, apoptosis, and migration of murine claudin-low mammary tumor cells.BMC Cancer 16:359 (2016).
PubMed: 27282619
Laohaviroj M et al.Clinicopathological Significance of Osteopontin in Cholangiocarcinoma Cases.Asian Pac J Cancer Prev 17:201-5 (2016).
PubMed: 26838210
Yan B et al.mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation.Nat Commun 7:11151 (2016).
PubMed: 27039827
Jiang S et al.Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway.Mol Med Rep 14:1891-900 (2016).
WB
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Human
.
PubMed: 27432616
Feng W et al.Apocynin attenuates angiotensin II-induced vascular smooth muscle cells osteogenic switching via suppressing extracellular signal-regulated kinase 1/2.Oncotarget 7:83588-83600 (2016).
WB
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Rat
.
PubMed: 27835878
Suzuki H et al.Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis.Proc Natl Acad Sci U S A 113:7840-5 (2016).
IHC-Fr
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Rat
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PubMed: 27370800
Dang PN et al.Controlled Dual Growth Factor Delivery From Microparticles Incorporated Within Human Bone Marrow-Derived Mesenchymal Stem Cell Aggregates for Enhanced Bone Tissue Engineering via Endochondral Ossification.Stem Cells Transl Med 5:206-17 (2016).
Human
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PubMed: 26702127
Spina A et al.NZ-GMP Approved Serum Improve hDPSC Osteogenic Commitment and Increase Angiogenic Factor Expression.Front Physiol 7:354 (2016).
ICC/IF
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Human
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PubMed: 27594842
Qu X et al.MiR-132-3p Regulates the Osteogenic Differentiation of Thoracic Ligamentum Flavum Cells by Inhibiting Multiple Osteogenesis-Related Genes.Int J Mol Sci 17:N/A (2016).
WB
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Human
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PubMed: 27556448
Liang Q et al.An Explanation of the Underlying Mechanisms for the In Vitro and In Vivo Antiurolithic Activity of Glechoma longituba.Oxid Med Cell Longev 2016:3134919 (2016).
PubMed: 27840669
Manda KR et al.NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence.Oncogene 35:3282-92 (2016).
PubMed: 26477312
Hira VV et al.CD133+ and Nestin+ Glioma Stem-Like Cells Reside Around CD31+ Arterioles in Niches that Express SDF-1a, CXCR4, Osteopontin and Cathepsin K.J Histochem Cytochem 63:481-93 (2015).
PubMed: 25809793
Crabbé A et al.Recellularization of decellularized lung scaffolds is enhanced by dynamic suspension culture.PLoS One 10:e0126846 (2015).
IHC-P
;
Mouse
.
PubMed: 25962111
Lin CN et al.The significance of the co-existence of osteopontin and tumor-associated macrophages in gastric cancer progression.BMC Cancer 15:128 (2015).
IHC-P
;
Human
.
PubMed: 25872762
Bu X et al.Effects of "Danzhi Decoction" on Chronic Pelvic Pain, Hemodynamics, and Proinflammatory Factors in the Murine Model of Sequelae of Pelvic Inflammatory Disease.Evid Based Complement Alternat Med 2015:547251 (2015).
WB
;
Mouse
.
PubMed: 27087818
Gong X et al.Microvascular density and vascular endothelial growth factor and osteopontin expression during the implantation window in a controlled ovarian hyperstimulation rat model.Exp Ther Med 9:773-779 (2015).
WB
;
Rat
.
PubMed: 25667627
Li X et al.The selective NADPH oxidase inhibitor apocynin has potential prophylactic effects on melamine-related nephrolithiasis in vitro and in vivo.Mol Cell Biochem 399:167-78 (2015).
PubMed: 25318609
Mohamed IA et al.Na+/H+ exchanger isoform 1-induced osteopontin expression facilitates cardiomyocyte hypertrophy.PLoS One 10:e0123318 (2015).
WB
;
Rat
.
PubMed: 25884410
Wu Y et al.TrAmplification of Human Dental Follicle Cells by piggyBac Transposon - Mediated Reversible Immortalization System.PLoS One 10:e0130937 (2015).
WB
;
Human
.
PubMed: 26172849
Matsue Y et al.Serum osteopontin predicts degree of hepatic fibrosis and serves as a biomarker in patients with hepatitis C virus infection.PLoS One 10:e0118744 (2015).
IHC
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Human
.
PubMed: 25760884
Sepe R et al.CBX7 and HMGA1b proteins act in opposite way on the regulation of the SPP1 gene expression.Oncotarget 6:2680-92 (2015).
WB
.
PubMed: 25595895
Li X et al.Potential Mechanisms Responsible for the Antinephrolithic Effects of an Aqueous Extract of Fructus Aurantii.Evid Based Complement Alternat Med 2015:491409 (2015).
IHC
.
PubMed: 26170875
Zhang S et al.Plumbagin protects against glucocorticoid-induced osteoporosis through Nrf-2 pathway.Cell Stress Chaperones 20:621-9 (2015).
PubMed: 25939783
Ressler SJ et al.WFDC1 is a key modulator of inflammatory and wound repair responses.Am J Pathol 184:2951-64 (2014).
PubMed: 25219356
Wu M et al.Deletion of core-binding factor ß (Cbfß) in mesenchymal progenitor cells provides new insights into Cbfß/Runxs complex function in cartilage and bone development.Bone 65:49-59 (2014).
PubMed: 24798493
Albertsson AM et al.The effect of osteopontin and osteopontin-derived peptides on preterm brain injury.J Neuroinflammation 11:197 (2014).
WB
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Mouse
.
PubMed: 25465048
Ellam T et al.Vitamin D deficiency and exogenous vitamin D excess similarly increase diffuse atherosclerotic calcification in apolipoprotein E knockout mice.PLoS One 9:e88767 (2014).
IHC-P
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Mouse
.
PubMed: 24586387
Wang H et al.Polycystin-1 mediates mechanical strain-induced osteoblastic mechanoresponses via potentiation of intracellular calcium and Akt/ß-catenin pathway.PLoS One 9:e91730 (2014).
Mouse
.
PubMed: 24618832
Neumann C et al.Osteopontin is induced by TGF-ß2 and regulates metabolic cell activity in cultured human optic nerve head astrocytes.PLoS One 9:e92762 (2014).
WB
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Human
.
PubMed: 24718314
Lee J et al.Rewiring mesenchymal stem cell lineage specification by switching the biophysical microenvironment.Sci Rep 4:5188 (2014).
Human
.
PubMed: 24898422
Su Z et al.Up-regulated HMGB1 in EAM directly led to collagen deposition by a PKCß/Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB1.J Cell Mol Med 18:1740-51 (2014).
WB
;
Mouse
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PubMed: 24912759
Abu El-Asrar AM et al.S100A4 is upregulated in proliferative diabetic retinopathy and correlates with markers of angiogenesis and fibrogenesis.Mol Vis 20:1209-24 (2014).
WB
;
Rat
.
PubMed: 25253987
Lu C et al.Targeted deletion of growth hormone (GH) receptor in macrophage reveals novel osteopontin-mediated effects of GH on glucose homeostasis and insulin sensitivity in diet-induced obesity.J Biol Chem 288:15725-35 (2013).
Mouse
.
PubMed: 23595986
Chiba H et al.Diabetes impairs the interactions between long-term hematopoietic stem cells and osteopontin-positive cells in the endosteal niche of mouse bone marrow.Am J Physiol Cell Physiol 305:C693-703 (2013).
IHC-FoFr
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Mouse
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PubMed: 23885062
Yang HY et al.Proteomic analysis of gingival tissue and alveolar bone during alveolar bone healing.Mol Cell Proteomics 12:2674-88 (2013).
IHC
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Pig
.
PubMed: 23824910
Fudge NJ & Mearow KM Extracellular matrix-associated gene expression in adult sensory neuron populations cultured on a laminin substrate.BMC Neurosci 14:15 (2013).
PubMed: 23360524
Foudah D et al.Human mesenchymal stem cells express neuronal markers after osteogenic and adipogenic differentiation.Cell Mol Biol Lett 18:163-86 (2013).
PubMed: 23430457
Jiang Y et al.OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population.Arthritis Res Ther 15:R3 (2013).
WB
.
PubMed: 23289928
Morales-Ibanez O et al.Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis.Hepatology 58:1742-56 (2013).
PubMed: 23729174
Kockar F et al.Hypoxia and cytokines regulate carbonic anhydrase 9 expression in hepatocellular carcinoma cells in vitro.World J Clin Oncol 3:82-91 (2012).
PubMed: 22724087
Said HM et al.Inhibition of N-Myc down regulated gene 1 in in vitro cultured human glioblastoma cells.World J Clin Oncol 3:104-10 (2012).
PubMed: 22787578
Chaen T et al.Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.PLoS One 7:e48933 (2012).
IHC
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PubMed: 23152823
Strauß S et al.Induction of osteogenic differentiation of adipose derived stem cells by microstructured nitinol actuator-mediated mechanical stress.PLoS One 7:e51264 (2012).
ICC
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Human
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PubMed: 23236461
Hapangama DK et al.Aberrant expression of metastasis-inducing proteins in ectopic and matched eutopic endometrium of women with endometriosis: implications for the pathogenesis of endometriosis.Hum Reprod 27:394-407 (2012).
WB
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Human
.
PubMed: 22147918
Tachibana H et al.Activation of liver X receptor inhibits osteopontin and ameliorates diabetic nephropathy.J Am Soc Nephrol 23:1835-46 (2012).
WB, IHC-Fr
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Mouse
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PubMed: 23085633
Paliwal P et al.Age dependent increase in the levels of osteopontin inhibits skeletal muscle regeneration.Aging (Albany NY) 4:553-66 (2012).
WB
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PubMed: 22915705
Reticker-Flynn NE et al.A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis.Nat Commun 3:1122 (2012).
WB, IHC
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Mouse
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PubMed: 23047680
Zhu H et al.Controlled growth and differentiation of MSCs on grooved films assembled from monodisperse biological nanofibers with genetically tunable surface chemistries.Biomaterials 32:4744-52 (2011).
ICC/IF
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Rat
.
PubMed: 21507480
El-Asrar AM et al.Expression of high-mobility groups box-1/receptor for advanced glycation end products/osteopontin/early growth response-1 pathway in proliferative vitreoretinal epiretinal membranes.Mol Vis 17:508-18 (2011).
PubMed: 21365018
Clewes O et al.Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)-Characterization and Directed Differentiation into Osteocytes and Melanocytes.Stem Cell Rev 7:799-814 (2011).
ICC
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Human
.
PubMed: 21455606
Cheng CC et al.Bronchiolitis obliterans organizing pneumonia in Swine associated with porcine circovirus type 2 infection.J Biomed Biotechnol 2011:245728 (2011).
PubMed: 20976305
Birke MT et al.Changes of osteopontin in the aqueous humor of the DBA2/J glaucoma model correlated with optic nerve and RGC degenerations.Invest Ophthalmol Vis Sci 51:5759-67 (2010).
PubMed: 20574028
Song YR et al.Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney.Nephrol Dial Transplant 25:77-85 (2010).
IHC-P
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Rat
.
PubMed: 19737871
Sreekanthreddy P et al.Identification of potential serum biomarkers of glioblastoma: serum osteopontin levels correlate with poor prognosis.Cancer Epidemiol Biomarkers Prev 19:1409-22 (2010).
IHC-P
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Human
.
PubMed: 20530493
Wine E et al.Osteopontin Mediates Citrobacter rodentium-Induced Colonic Epithelial Cell Hyperplasia and Attaching-Effacing Lesions.Am J Pathol 177:1320-32 (2010).
IHC-P
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Mouse
.
PubMed: 20651246
Ricchiuti V et al.Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats.J Endocrinol 200:75-84 (2009).
PubMed: 18931023
Gould Rothberg BE et al.Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis.J Natl Cancer Inst 101:452-74 (2009).
PubMed: 19318635
Banerjee A et al.The influence of estrogen on hepatobiliary osteopontin (SPP1) expression in a female rodent model of alcoholic steatohepatitis.Toxicol Pathol 37:492-501 (2009).
PubMed: 19387089
Rose P et al.Genes overexpressed in cerebral arteries following salt-induced hypertensive disease are regulated by angiotensin II, JunB, and CREB.Am J Physiol Heart Circ Physiol 294:H1075-85 (2008).
PubMed: 18156195
Jäger A et al.Cellular and extracellular factors in early root resorption repair in the rat.Eur J Orthod 30:336-45 (2008).
PubMed: 18632841
Finak G et al.Stromal gene expression predicts clinical outcome in breast cancer.Nat Med 14:518-27 (2008).
PubMed: 18438415
Said HM et al.Expression patterns of the hypoxia-related genes osteopontin, CA9, erythropoietin, VEGF and HIF-1alpha in human glioma in vitro and in vivo.Radiother Oncol 83:398-405 (2007).
PubMed: 17524506
Kadkol SS et al.Osteopontin expression and serum levels in metastatic uveal melanoma: a pilot study.Invest Ophthalmol Vis Sci 47:802-6 (2006).
IHC-P
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Human
.
PubMed: 16505010
Jang T et al.Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea.Am J Pathol 168:1676-85 (2006).
PubMed: 16651633
Madoz-Gúrpide J et al.Proteomics-based validation of genomic data: applications in colorectal cancer diagnosis.Mol Cell Proteomics 5:1471-83 (2006).
PubMed: 16733264
Packer L et al.Osteopontin is a downstream effector of the PI3-kinase pathway in melanomas that is inversely correlated with functional PTEN.Carcinogenesis 27:1778-86 (2006).
PubMed: 16571650
Pardo A et al.Up-regulation and profibrotic role of osteopontin in human idiopathic pulmonary fibrosis.PLoS Med 2:e251 (2005).
PubMed: 16128620
Li Q et al.Potential roles of follicular dendritic cell-associated osteopontin in lymphoid follicle pathology and repair and in B cell regulation in HIV-1 and SIV infection.J Infect Dis 192:1269-76 (2005).
PubMed: 16136472
Said HM et al.Response of the plasma hypoxia marker osteopontin to in vitro hypoxia in human tumor cells.Radiother Oncol 76:200-5 (2005).
PubMed: 16024111
Hall MR et al.Temporal regulation of venous extracellular matrix components during arteriovenous fistula maturation.J Vasc Access 16:93-106 (0).
PubMed: 25262757
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