Anti-Osteopontin antibody (ab8448)

ab8448 has been referenced in 74 publications.

• Dickerson MT  et al. Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic ß-cells. PLoS One 12:e0175069 (2017). ICC/IF ; Mouse . PubMed: 28403169
• Corciulo C  et al. Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression. Nat Commun 8:15019 (2017). Mouse, Rat . PubMed: 28492224
• Luo G  et al. Icariside II promotes the osteogenic differentiation of canine bone marrow mesenchymal stem cells via the PI3K/AKT/mTOR/S6K1 signaling pathways. Am J Transl Res 9:2077-2087 (2017). PubMed: 28559962
• Lee SH  et al. Effect of Rosuvastatin on Bovine Pericardial Aortic Tissue Valve Calcification in a Rat Subdermal Implantation Model. Korean Circ J 47:401-408 (2017). PubMed: 28567091
• Liang Q  et al. An Explanation of the Underlying Mechanisms for the In Vitro and In Vivo Antiurolithic Activity of Glechoma longituba. Oxid Med Cell Longev 2016:3134919 (2016). PubMed: 27840669
• Manda KR  et al. NFATc1 promotes prostate tumorigenesis and overcomes PTEN loss-induced senescence. Oncogene 35:3282-92 (2016). PubMed: 26477312
• Saleh S  et al. Osteopontin regulates proliferation, apoptosis, and migration of murine claudin-low mammary tumor cells. BMC Cancer 16:359 (2016). PubMed: 27282619
• Laohaviroj M  et al. Clinicopathological Significance of Osteopontin in Cholangiocarcinoma Cases. Asian Pac J Cancer Prev 17:201-5 (2016). PubMed: 26838210
• Yan B  et al. mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation. Nat Commun 7:11151 (2016). PubMed: 27039827
• Jiang S  et al. Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway. Mol Med Rep 14:1891-900 (2016). WB ; Human . PubMed: 27432616
• Feng W  et al. Apocynin attenuates angiotensin II-induced vascular smooth muscle cells osteogenic switching via suppressing extracellular signal-regulated kinase 1/2. Oncotarget 7:83588-83600 (2016). WB ; Rat . PubMed: 27835878
• Suzuki H  et al. Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis. Proc Natl Acad Sci U S A 113:7840-5 (2016). IHC-Fr ; Rat . PubMed: 27370800
• Dang PN  et al. Controlled Dual Growth Factor Delivery From Microparticles Incorporated Within Human Bone Marrow-Derived Mesenchymal Stem Cell Aggregates for Enhanced Bone Tissue Engineering via Endochondral Ossification. Stem Cells Transl Med 5:206-17 (2016). Human . PubMed: 26702127
• Spina A  et al. NZ-GMP Approved Serum Improve hDPSC Osteogenic Commitment and Increase Angiogenic Factor Expression. Front Physiol 7:354 (2016). ICC/IF ; Human . PubMed: 27594842
• Qu X  et al. MiR-132-3p Regulates the Osteogenic Differentiation of Thoracic Ligamentum Flavum Cells by Inhibiting Multiple Osteogenesis-Related Genes. Int J Mol Sci 17:N/A (2016). WB ; Human . PubMed: 27556448
• Crabbé A  et al. Recellularization of decellularized lung scaffolds is enhanced by dynamic suspension culture. PLoS One 10:e0126846 (2015). IHC-P ; Mouse . PubMed: 25962111
• Lin CN  et al. The significance of the co-existence of osteopontin and tumor-associated macrophages in gastric cancer progression. BMC Cancer 15:128 (2015). IHC-P ; Human . PubMed: 25872762
• Bu X  et al. Effects of "Danzhi Decoction" on Chronic Pelvic Pain, Hemodynamics, and Proinflammatory Factors in the Murine Model of Sequelae of Pelvic Inflammatory Disease. Evid Based Complement Alternat Med 2015:547251 (2015). WB ; Mouse . PubMed: 27087818
• Gong X  et al. Microvascular density and vascular endothelial growth factor and osteopontin expression during the implantation window in a controlled ovarian hyperstimulation rat model. Exp Ther Med 9:773-779 (2015). WB ; Rat . PubMed: 25667627
• Li X  et al. The selective NADPH oxidase inhibitor apocynin has potential prophylactic effects on melamine-related nephrolithiasis in vitro and in vivo. Mol Cell Biochem 399:167-78 (2015). PubMed: 25318609
• Mohamed IA  et al. Na+/H+ exchanger isoform 1-induced osteopontin expression facilitates cardiomyocyte hypertrophy. PLoS One 10:e0123318 (2015). WB ; Rat . PubMed: 25884410
• Wu Y  et al. TrAmplification of Human Dental Follicle Cells by piggyBac Transposon - Mediated Reversible Immortalization System. PLoS One 10:e0130937 (2015). WB ; Human . PubMed: 26172849
• Matsue Y  et al. Serum osteopontin predicts degree of hepatic fibrosis and serves as a biomarker in patients with hepatitis C virus infection. PLoS One 10:e0118744 (2015). IHC ; Human . PubMed: 25760884
• Sepe R  et al. CBX7 and HMGA1b proteins act in opposite way on the regulation of the SPP1 gene expression. Oncotarget 6:2680-92 (2015). WB . PubMed: 25595895
• Li X  et al. Potential Mechanisms Responsible for the Antinephrolithic Effects of an Aqueous Extract of Fructus Aurantii. Evid Based Complement Alternat Med 2015:491409 (2015). IHC . PubMed: 26170875
• Zhang S  et al. Plumbagin protects against glucocorticoid-induced osteoporosis through Nrf-2 pathway. Cell Stress Chaperones 20:621-9 (2015). PubMed: 25939783
• Hira VV  et al. CD133+ and Nestin+ Glioma Stem-Like Cells Reside Around CD31+ Arterioles in Niches that Express SDF-1a, CXCR4, Osteopontin and Cathepsin K. J Histochem Cytochem 63:481-93 (2015). PubMed: 25809793
• Ressler SJ  et al. WFDC1 is a key modulator of inflammatory and wound repair responses. Am J Pathol 184:2951-64 (2014). PubMed: 25219356
• Wu M  et al. Deletion of core-binding factor ß (Cbfß) in mesenchymal progenitor cells provides new insights into Cbfß/Runxs complex function in cartilage and bone development. Bone 65:49-59 (2014). PubMed: 24798493
• Albertsson AM  et al. The effect of osteopontin and osteopontin-derived peptides on preterm brain injury. J Neuroinflammation 11:197 (2014). WB ; Mouse . PubMed: 25465048
• Ellam T  et al. Vitamin D deficiency and exogenous vitamin D excess similarly increase diffuse atherosclerotic calcification in apolipoprotein E knockout mice. PLoS One 9:e88767 (2014). IHC-P ; Mouse . PubMed: 24586387
• Wang H  et al. Polycystin-1 mediates mechanical strain-induced osteoblastic mechanoresponses via potentiation of intracellular calcium and Akt/ß-catenin pathway. PLoS One 9:e91730 (2014). Mouse . PubMed: 24618832
• Neumann C  et al. Osteopontin is induced by TGF-ß2 and regulates metabolic cell activity in cultured human optic nerve head astrocytes. PLoS One 9:e92762 (2014). WB ; Human . PubMed: 24718314
• Lee J  et al. Rewiring mesenchymal stem cell lineage specification by switching the biophysical microenvironment. Sci Rep 4:5188 (2014). Human . PubMed: 24898422
• Su Z  et al. Up-regulated HMGB1 in EAM directly led to collagen deposition by a PKCß/Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB1. J Cell Mol Med 18:1740-51 (2014). WB ; Mouse . PubMed: 24912759
• Abu El-Asrar AM  et al. S100A4 is upregulated in proliferative diabetic retinopathy and correlates with markers of angiogenesis and fibrogenesis. Mol Vis 20:1209-24 (2014). WB ; Rat . PubMed: 25253987
• Lu C  et al. Targeted deletion of growth hormone (GH) receptor in macrophage reveals novel osteopontin-mediated effects of GH on glucose homeostasis and insulin sensitivity in diet-induced obesity. J Biol Chem 288:15725-35 (2013). Mouse . PubMed: 23595986
• Chiba H  et al. Diabetes impairs the interactions between long-term hematopoietic stem cells and osteopontin-positive cells in the endosteal niche of mouse bone marrow. Am J Physiol Cell Physiol 305:C693-703 (2013). IHC-FoFr ; Mouse . PubMed: 23885062
• Yang HY  et al. Proteomic analysis of gingival tissue and alveolar bone during alveolar bone healing. Mol Cell Proteomics 12:2674-88 (2013). IHC ; Pig . PubMed: 23824910
• Fudge NJ & Mearow KM Extracellular matrix-associated gene expression in adult sensory neuron populations cultured on a laminin substrate. BMC Neurosci 14:15 (2013). PubMed: 23360524
• Foudah D  et al. Human mesenchymal stem cells express neuronal markers after osteogenic and adipogenic differentiation. Cell Mol Biol Lett 18:163-86 (2013). PubMed: 23430457
• Jiang Y  et al. OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population. Arthritis Res Ther 15:R3 (2013). WB . PubMed: 23289928
• Morales-Ibanez O  et al. Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis. Hepatology 58:1742-56 (2013). PubMed: 23729174
• Kockar F  et al. Hypoxia and cytokines regulate carbonic anhydrase 9 expression in hepatocellular carcinoma cells in vitro. World J Clin Oncol 3:82-91 (2012). PubMed: 22724087
• Said HM  et al. Inhibition of N-Myc down regulated gene 1 in in vitro cultured human glioblastoma cells. World J Clin Oncol 3:104-10 (2012). PubMed: 22787578
• Chaen T  et al. Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence. PLoS One 7:e48933 (2012). IHC . PubMed: 23152823
• Strauß S  et al. Induction of osteogenic differentiation of adipose derived stem cells by microstructured nitinol actuator-mediated mechanical stress. PLoS One 7:e51264 (2012). ICC ; Human . PubMed: 23236461
• Hapangama DK  et al. Aberrant expression of metastasis-inducing proteins in ectopic and matched eutopic endometrium of women with endometriosis: implications for the pathogenesis of endometriosis. Hum Reprod 27:394-407 (2012). WB ; Human . PubMed: 22147918
• Tachibana H  et al. Activation of liver X receptor inhibits osteopontin and ameliorates diabetic nephropathy. J Am Soc Nephrol 23:1835-46 (2012). WB, IHC-Fr ; Mouse . PubMed: 23085633
• Paliwal P  et al. Age dependent increase in the levels of osteopontin inhibits skeletal muscle regeneration. Aging (Albany NY) 4:553-66 (2012). WB . PubMed: 22915705
• Reticker-Flynn NE  et al. A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nat Commun 3:1122 (2012). WB, IHC ; Mouse . PubMed: 23047680
• Zhu H  et al. Controlled growth and differentiation of MSCs on grooved films assembled from monodisperse biological nanofibers with genetically tunable surface chemistries. Biomaterials 32:4744-52 (2011). ICC/IF ; Rat . PubMed: 21507480
• El-Asrar AM  et al. Expression of high-mobility groups box-1/receptor for advanced glycation end products/osteopontin/early growth response-1 pathway in proliferative vitreoretinal epiretinal membranes. Mol Vis 17:508-18 (2011). PubMed: 21365018
• Clewes O  et al. Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)-Characterization and Directed Differentiation into Osteocytes and Melanocytes. Stem Cell Rev 7:799-814 (2011). ICC ; Human . PubMed: 21455606
• Cheng CC  et al. Bronchiolitis obliterans organizing pneumonia in Swine associated with porcine circovirus type 2 infection. J Biomed Biotechnol 2011:245728 (2011). PubMed: 20976305
• Birke MT  et al. Changes of osteopontin in the aqueous humor of the DBA2/J glaucoma model correlated with optic nerve and RGC degenerations. Invest Ophthalmol Vis Sci 51:5759-67 (2010). PubMed: 20574028
• Song YR  et al. Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney. Nephrol Dial Transplant 25:77-85 (2010). IHC-P ; Rat . PubMed: 19737871
• Sreekanthreddy P  et al. Identification of potential serum biomarkers of glioblastoma: serum osteopontin levels correlate with poor prognosis. Cancer Epidemiol Biomarkers Prev 19:1409-22 (2010). IHC-P ; Human . PubMed: 20530493
• Wine E  et al. Osteopontin Mediates Citrobacter rodentium-Induced Colonic Epithelial Cell Hyperplasia and Attaching-Effacing Lesions. Am J Pathol 177:1320-32 (2010). IHC-P ; Mouse . PubMed: 20651246
• Ricchiuti V  et al. Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats. J Endocrinol 200:75-84 (2009). PubMed: 18931023
• Gould Rothberg BE  et al. Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis. J Natl Cancer Inst 101:452-74 (2009). PubMed: 19318635
• Banerjee A  et al. The influence of estrogen on hepatobiliary osteopontin (SPP1) expression in a female rodent model of alcoholic steatohepatitis. Toxicol Pathol 37:492-501 (2009). PubMed: 19387089
• Rose P  et al. Genes overexpressed in cerebral arteries following salt-induced hypertensive disease are regulated by angiotensin II, JunB, and CREB. Am J Physiol Heart Circ Physiol 294:H1075-85 (2008). PubMed: 18156195
• Jäger A  et al. Cellular and extracellular factors in early root resorption repair in the rat. Eur J Orthod 30:336-45 (2008). PubMed: 18632841
• Finak G  et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat Med 14:518-27 (2008). PubMed: 18438415
• Said HM  et al. Expression patterns of the hypoxia-related genes osteopontin, CA9, erythropoietin, VEGF and HIF-1alpha in human glioma in vitro and in vivo. Radiother Oncol 83:398-405 (2007). PubMed: 17524506
• Kadkol SS  et al. Osteopontin expression and serum levels in metastatic uveal melanoma: a pilot study. Invest Ophthalmol Vis Sci 47:802-6 (2006). IHC-P ; Human . PubMed: 16505010
• Jang T  et al. Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea. Am J Pathol 168:1676-85 (2006). PubMed: 16651633
• Madoz-Gúrpide J  et al. Proteomics-based validation of genomic data: applications in colorectal cancer diagnosis. Mol Cell Proteomics 5:1471-83 (2006). PubMed: 16733264
• Packer L  et al. Osteopontin is a downstream effector of the PI3-kinase pathway in melanomas that is inversely correlated with functional PTEN. Carcinogenesis 27:1778-86 (2006). PubMed: 16571650
• Pardo A  et al. Up-regulation and profibrotic role of osteopontin in human idiopathic pulmonary fibrosis. PLoS Med 2:e251 (2005). PubMed: 16128620
• Li Q  et al. Potential roles of follicular dendritic cell-associated osteopontin in lymphoid follicle pathology and repair and in B cell regulation in HIV-1 and SIV infection. J Infect Dis 192:1269-76 (2005). PubMed: 16136472
• Said HM  et al. Response of the plasma hypoxia marker osteopontin to in vitro hypoxia in human tumor cells. Radiother Oncol 76:200-5 (2005). PubMed: 16024111
• Hall MR  et al. Temporal regulation of venous extracellular matrix components during arteriovenous fistula maturation. J Vasc Access 16:93-106 (0). PubMed: 25262757