Overview

  • Product nameAnti-OTOA antibody
  • Description
    Rabbit polyclonal to OTOA
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 99-127 of Human OTOA (NP_733764.1, NP_001155155.1).

  • Positive control
    • Mouse liver tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab107640 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 129 kDa.

Target

  • FunctionMay act as an adhesion molecule.
  • Involvement in diseaseDefects in OTOA are the cause of deafness autosomal recessive type 22 (DFNB22) [MIM:607039]. DFNB22 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • Sequence similaritiesBelongs to the stereocilin family.
  • Cellular localizationApical cell membrane. Secreted > extracellular space > extracellular matrix. At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cancer/testis antigen 108 antibody
    • CT108 antibody
    • Deafness, autosomal recessive 22 antibody
    • DFNB22 antibody
    • FLJ32773 antibody
    • MGC157747 antibody
    • MGC39813 antibody
    • OTOA antibody
    • OTOAN_HUMAN antibody
    • Otoancorin antibody
    see all

Anti-OTOA antibody images

  • Anti-OTOA antibody (ab107640) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 129 kDa

References for Anti-OTOA antibody (ab107640)

ab107640 has not yet been referenced specifically in any publications.

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