Overview

  • Product name
    Anti-OTOP1 antibody
  • Description
    Rabbit polyclonal to OTOP1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 367-396 of Human OTOP1 (NP_819056.1).

  • Positive control
    • Mouse heart tissue lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab110975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 67 kDa.

Target

  • Function
    Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP.
  • Sequence similarities
    Belongs to the otopetrin family.
  • Cellular localization
    Membrane. Secreted > extracellular space. Detected in the gelatinous membrane overlying the inner ear macular epithelium.
  • Information by UniProt
  • Database links
  • Alternative names
    • A530025J20Rik antibody
    • otop1 antibody
    • OTOP1_HUMAN antibody
    • Otopetrin-1 antibody
    • Otp1 antibody
    • Tilted antibody
    • tlt antibody
    see all

Images

  • Anti-OTOP1 antibody (ab110975) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

    Predicted band size : 67 kDa

References

ab110975 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab110975.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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