WB: Preliminary experiments in human lysates of cell lines HeLa and HepG2 gave no specific signal but low background (at antibody concentration up to 1 µg/ml). We would appreciate any feedback from researchers regarding results obtained using this antibody for Western blot and any other applications?
FunctionHas deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin.
Sequence similaritiesBelongs to the peptidase C64 family. Contains 1 A20-type zinc finger. Contains 1 OTU domain.