Anti-Otx1 + Otx2 antibody - ChIP Grade (ab21990)

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ab21990 has been referenced in 43 publications.

  • Paik EJ  et al. Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture. Sci Rep 8:804 (2018). PubMed: 29339826
  • Tu J  et al. MicroRNA profiling during directed differentiation of cortical interneurons from human-induced pluripotent stem cells. FEBS Open Bio 8:502-512 (2018). PubMed: 29632804
  • Liu Y  et al. Regulated differentiation of WERI-Rb-1 cells into retinal neuron-like cells. Int J Mol Med 40:1172-1184 (2017). PubMed: 28848998
  • Lancaster MA  et al. Guided self-organization and cortical plate formation in human brain organoids. Nat Biotechnol 35:659-666 (2017). PubMed: 28562594
  • Takata N  et al. Self-patterning of rostral-caudal neuroectoderm requires dual role of Fgf signaling for localized Wnt antagonism. Nat Commun 8:1339 (2017). PubMed: 29109536
  • Sanges D  et al. Reprogramming Müller glia via in vivo cell fusion regenerates murine photoreceptors. J Clin Invest 126:3104-3116 (2016). IHC-P ; Mouse . PubMed: 27427986
  • Bernard C  et al. A Mouse Model for Conditional Secretion of Specific Single-Chain Antibodies Provides Genetic Evidence for Regulation of Cortical Plasticity by a Non-cell Autonomous Homeoprotein Transcription Factor. PLoS Genet 12:e1006035 (2016). IP . PubMed: 27171438
  • Jager P  et al. Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus. Nat Commun 7:13579 (2016). PubMed: 27929058
  • Marcos S  et al. Meis1 coordinates a network of genes implicated in eye development and microphthalmia. Development 142:3009-20 (2015). PubMed: 26253404
  • Kaur R  et al. OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells. Dis Model Mech 8:1295-309 (2015). WB . PubMed: 26398939
  • Mortensen AH  et al. Deletion of OTX2 in neural ectoderm delays anterior pituitary development. Hum Mol Genet 24:939-53 (2015). PubMed: 25315894
  • Nagel S  et al. Aberrantly Expressed OTX Homeobox Genes Deregulate B-Cell Differentiation in Hodgkin Lymphoma. PLoS One 10:e0138416 (2015). WB ; Human . PubMed: 26406991
  • García-Castro IL  et al. Markers of Pluripotency in Human Amniotic Epithelial Cells and Their Differentiation to Progenitor of Cortical Neurons. PLoS One 10:e0146082 (2015). ICC . PubMed: 26720151
  • Xie BB  et al. Differentiation of retinal ganglion cells and photoreceptor precursors from mouse induced pluripotent stem cells carrying an Atoh7/Math5 lineage reporter. PLoS One 9:e112175 (2014). ICC/IF ; Mouse . PubMed: 25401462
  • Bertolesi GE  et al. Wiring the retinal circuits activated by light during early development. Neural Dev 9:3 (2014). ICC/IF ; Xenopus laevis . PubMed: 24521229
  • Masuda T  et al. Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium. J Biol Chem 289:12908-21 (2014). PubMed: 24634209
  • Kim N  et al. Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex. F1000Res 3:178 (2014). PubMed: 25165539
  • Emerson MM  et al. Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors. Dev Cell 26:59-72 (2013). PubMed: 23867227
  • Yang J  et al. Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development. Development 140:1342-52 (2013). Mouse . PubMed: 23444360
  • Zhu Y  et al. Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium. PLoS One 8:e54552 (2013). ICC/IF ; Human . PubMed: 23358448
  • Sanges D  et al. Wnt/ß-catenin signaling triggers neuron reprogramming and regeneration in the mouse retina. Cell Rep 4:271-86 (2013). PubMed: 23850287
  • Lancaster MA  et al. Cerebral organoids model human brain development and microcephaly. Nature 501:373-9 (2013). PubMed: 23995685
  • Zahabi A  et al. A new efficient protocol for directed differentiation of retinal pigmented epithelial cells from normal and retinal disease induced pluripotent stem cells. Stem Cells Dev 21:2262-72 (2012). PubMed: 22145677
  • Inoue F  et al. Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors. Mol Cell Biol 32:2618-27 (2012). PubMed: 22566684
  • Tseng WF  et al. An evolutionarily conserved kernel of gata5, gata6, otx2 and prdm1a operates in the formation of endoderm in zebrafish. Dev Biol 357:541-57 (2011). PubMed: 21756893
  • Addis RC  et al. Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. PLoS One 6:e28719 (2011). ICC/IF ; Mouse . PubMed: 22174877
  • Kameda Y  et al. Hes1 regulates the number and anterior-posterior patterning of mesencephalic dopaminergic neurons at the mid/hindbrain boundary (isthmus). Dev Biol 358:91-101 (2011). IHC-P ; Mouse . PubMed: 21798254
  • Greber B  et al. FGF signalling inhibits neural induction in human embryonic stem cells. EMBO J 30:4874-84 (2011). PubMed: 22085933
  • Bassett EA  et al. AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis. Hum Mol Genet 19:1791-804 (2010). IHC-P ; Mouse . PubMed: 20150232
  • Ono Y  et al. The basic helix-loop-helix transcription factor Nato3 controls neurogenic activity in mesencephalic floor plate cells. Development 137:1897-906 (2010). ICC/IF ; Mouse . PubMed: 20460368
  • Conte I  et al. Proper differentiation of photoreceptors and amacrine cells depends on a regulatory loop between NeuroD and Six6. Development 137:2307-17 (2010). IHC-Fr ; Chicken . PubMed: 20534668
  • Tang M  et al. Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons. J Neurosci 30:9280-91 (2010). PubMed: 20610763
  • Demarque M & Spitzer NC Activity-Dependent Expression of Lmx1b Regulates Specification of Serotonergic Neurons Modulating Swimming Behavior. Neuron 67:321-334 (2010). IHC-Fr ; Xenopus laevis . PubMed: 20670838
  • Masuda T & Esumi N SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium. J Biol Chem 285:26933-44 (2010). ChIP ; Cow . PubMed: 20530484
  • Suda Y  et al. The same enhancer regulates the earliest Emx2 expression in caudal forebrain primordium, subsequent expression in dorsal telencephalon and later expression in the cortical ventricular zone. Development 137:2939-49 (2010). ChIP ; Mouse . PubMed: 20667915
  • Esumi N  et al. BEST1 expression in the retinal pigment epithelium is modulated by OTX family members. Hum Mol Genet 18:128-41 (2009). WB, ChIP ; Cow . PubMed: 18849347
  • Larder R & Mellon PL Otx2 Induction of the Gonadotropin-releasing Hormone Promoter Is Modulated by Direct Interactions with Grg Co-repressors. J Biol Chem 284:16966-78 (2009). WB, ChIP . PubMed: 19401468
  • Tackenberg MA  et al. Müller cell activation, proliferation and migration following laser injury. Mol Vis 15:1886-96 (2009). IHC-Fr ; Mouse . PubMed: 19768129
  • Ruby KM & Zheng B Gene targeting in a HUES line of human embryonic stem cells via electroporation. Stem Cells 27:1496-506 (2009). ICC/IF ; Human . PubMed: 19544466
  • Danno H  et al. Molecular links among the causative genes for ocular malformation: Otx2 and Sox2 coregulate Rax expression. Proc Natl Acad Sci U S A 105:5408-13 (2008). WB ; Xenopus laevis . PubMed: 18385377
  • Ogino H  et al. Convergence of a head-field selector Otx2 and Notch signaling: a mechanism for lens specification. Development 135:249-58 (2008). ChIP . PubMed: 18057103
  • ten Berge D  et al. Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell Stem Cell 3:508-18 (2008). IHC-FoFr ; Mouse . PubMed: 18983966
  • Binato R  et al. Otx2 is a putative candidate to activate mice Msx1 gene from distal enhancer. Biochem Biophys Res Commun 358:655-60 (2007). PubMed: 17499211


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