Overview

  • Product nameAnti-OVCA1 antibody
    See all OVCA1 primary antibodies
  • Description
    Rabbit polyclonal to OVCA1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (NQIPPEILKN PQLQAAIRVL PSNYNFEIPK TIWRIQQAQA KKVALQMPEG) of Human OVCA1 (NP_001374).

  • Positive control
    • RPMI-8226 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab101975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRequired for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a role in embryonic growth, organogenesis and postnatal survival.
  • Tissue specificityExpressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, mammary gland, colon, small intestine, testis and ovary. Reduced expression in primary breast and ovarian tumors.
  • Sequence similaritiesBelongs to the DPH1/DPH2 family. DPH1 subfamily.
  • Cellular localizationNucleus. Cytoplasm. Punctate, primarily perinuclear localization.
  • Information by UniProt
  • Database links
  • Alternative names
    • Candidate tumor suppressor in ovarian cancer 1 antibody
    • Diphthamide biosynthesis protein 1 antibody
    • Diphthamide biosynthesis protein 2 homolog like 1 antibody
    • Diphthamide biosynthesis protein 2 homolog-like 1 antibody
    • Diphthamide biosynthesis protein 2 like antibody
    • Diphthamide biosynthesis protein 2-like antibody
    • Diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces) like 1 antibody
    • Diptheria toxin resistance protein required for diphthamide biosynthesis like 1 antibody
    • DPH like 1 (S. cerevisiae) antibody
    • DPH like 1 antibody
    • DPH-like 1 antibody
    • DPH1 antibody
    • DPH1 homolog (S. cerevisiae) antibody
    • DPH1 homolog antibody
    • DPH1_HUMAN antibody
    • DPH2 like 1 antibody
    • DPH2-like 1 antibody
    • DPH2L antibody
    • DPH2L1 antibody
    • FLJ33211 antibody
    • HsDph1 antibody
    • Ovarian cancer associated gene 1 antibody
    • Ovarian cancer associated gene 1 protein antibody
    • Ovarian cancer-associated gene 1 protein antibody
    • Ovarian tumor suppressor candidate 1 antibody
    see all

Anti-OVCA1 antibody images

  • Anti-OVCA1 antibody (ab101975) at 1 µg/ml + RPMI-8226 cell lysate at 10 µg

    Predicted band size : 49 kDa

References for Anti-OVCA1 antibody (ab101975)

ab101975 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab101975.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"