Anti-OXSR1 (phospho T185) antibody (ab192803)

Overview

  • Product name
    Anti-OXSR1 (phospho T185) antibody
    See all OXSR1 primary antibodies
  • Description
    Rabbit polyclonal to OXSR1 (phospho T185)
  • Specificity
    ab192803 detects endogenous levels of OXSR1 only when phosphorylated at Threonine 185.
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human OXSR1 (phospho T185) conjugated to Keyhole Limpet Haemocyanin (KLH). Peptide sequence around phosphorylation site of threonine185(R-K-T(p)-F-V).
    Database link: O95747

  • Positive control
    • HepG2 cell extract; Human breast carcinoma tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 0.87% Sodium chloride, 49% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab192803 was purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab192803 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 58 kDa.
IHC-P 1/50 - 1/100.

Target

  • Function
    Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.
  • Tissue specificity
    Ubiquitously expressed in all tissue examined.
  • Sequence similarities
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2210022N24Rik antibody
    • 2810422B09Rik antibody
    • AI462649 antibody
    • AW209236 antibody
    • KIAA1101 antibody
    • mKIAA1101 antibody
    • OSR 1 antibody
    • OSR1 antibody
    • OTTHUMP00000209062 antibody
    • Oxidative stress responsive 1 antibody
    • Oxidative stress responsive 1 protein antibody
    • Oxidative stress-responsive 1 protein antibody
    • OXSR 1 antibody
    • OXSR1 antibody
    • OXSR1_HUMAN antibody
    • Serine/threonine protein kinase OSR1 antibody
    • Serine/threonine-protein kinase OSR1 antibody
    see all

Images

  • All lanes : Anti-OXSR1 (phospho T185) antibody (ab192803) at 1/500 dilution

    Lane 1 : HepG2 cell extract
    Lane 2 : HepG2 cell extract with antigen-specific peptide


    Predicted band size : 58 kDa
  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue labeling OXSR1 (phospho T185) with ab192803 at 1/50 (left) or ab192803 preincubated with blocking peptide (right).

References

ab192803 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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