Biological descriptionα1A and partial α2A adrenoceptor agonist. Ki values are 6, 320 and 390 nM for α1A, α1B and α1C, respectively. Vasoconstrictor.
Chemical name3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol hydrochloride
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
References for Oxymetazoline hydrochloride (ab120712)
This product has been referenced in:
Horie K et al. Selectivity of the imidazoline alpha-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned alpha 1-adrenoceptor subtypes. Br J Pharmacol116:1611-8 (1995).
Read more (PubMed: 8564227) »
Alberts P Subtype classification of the presynaptic alpha-adrenoceptors which regulate [3H]-noradrenaline secretion in guinea-pig isolated urethra. Br J Pharmacol105:142-6 (1992).
Read more (PubMed: 1317735) »