Anti-P cadherin antibody [56C1], prediluted (ab75442)


  • Product nameAnti-P cadherin antibody [56C1], prediluted
    See all P cadherin primary antibodies
  • Description
    Mouse monoclonal [56C1] to P cadherin, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant protein corresponding to extracellular domain of human P cadherin.

  • EpitopeExternal domain
  • Positive control
    • Human tonsil tissue



Our Abpromise guarantee covers the use of ab75442 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.


  • FunctionCadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • Tissue specificityExpressed in some normal epithelial tissues and in some carcinoma cell lines.
  • Involvement in diseaseDefects in CDH3 are the cause of hypotrichosis with juvenile macular dystrophy (HJMD) [MIM:601553]. HJMD is a rare autosomal recessive disorder characterized by early hair loss heralding severe degenerative changes of the retinal macula and culminating in blindness during the second to third decade of life.
    Defects in CDH3 are the cause of ectodermal dysplasia with ectrodactyly and macular dystrophy (EEM) [MIM:225280]; also known as EEM syndrome, Albrectsen-Svendsen syndrome or Ohdo-Hirayama-Terawaki syndrome. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EEM is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with macular dystrophy and ectrodactyly.
  • Sequence similaritiesContains 5 cadherin domains.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CADH3_HUMAN antibody
    • Cadherin 3 antibody
    • Cadherin 3 precursor antibody
    • Cadherin 3 type 1 antibody
    • Cadherin-3 antibody
    • Cadp antibody
    • Calcium dependent adhesion protein placental antibody
    • CDH 3 antibody
    • CDH3 antibody
    • CDH3 protein antibody
    • CDHP antibody
    • HJMD antibody
    • P cadherin (placental) antibody
    • P-cadherin antibody
    • PCAD antibody
    • Placental cadherin antibody
    see all

Anti-P cadherin antibody [56C1], prediluted images

  • Formalin-fixed, paraffin-embedded human tonsil stained with ab75442 using peroxidase conjugate and AEC chromogen. Note membrane staining of epithelial cells.

References for Anti-P cadherin antibody [56C1], prediluted (ab75442)

ab75442 has not yet been referenced specifically in any publications.

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Thank you for your reply.

I have contacted the lab about adding the undiluted version of ab75442 to the catalogue and I will let you know as soon as I can whether we are able to do this or not.

In the meantime if there is anything e...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (tonsil)
Specification tonsil
Fixative Formaldehyde
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: EDTA, 20 minutes 100C
Permeabilization No

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Submitted Dec 16 2009