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Product Name
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p150 CAF1 antibody [SS 1 1-13]
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See all p150 CAF1 antibodies (3)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [SS 1 1-13] to p150 CAF1
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Immunogen
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Recombinant full length protein (Human).
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Reacts with
(species key)
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Hu
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Specificity
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Specific for CAF-1p150
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Tested applications
(see key)
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IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IP: Use at an assay dependent dilution.
WB: 1/1000 (from reference PubMed: 17052464). Predicted molecular weight: 150 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Chromosome Structure >> Chromatin assembly
Chromatin and Nuclear Signaling >> Chromatin Remodeling >> Histone chaperones
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Relevance
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Chromatin assembly factor 1 (CAF1) is a member of the histone chaperone family. It is required for inheritance of epigenetically determined chromosomal states, and in vitro, it promotes the assembly of chromatin during DNA replication and DNA repair. CAF1 is a complex of three subunits; p150, p60, and p48. This complex is localized to the nucleus of human cells. Both the composition and the biochemical activity of CAF1 are conserved among human, yeast, and Drosophila.
Chromatin assembly factor 1 (CAF-1) is a member of the histone chaperone family. It is required for inheritance of epigenetically determined chromosomal states, and in vitro, it promotes the assembly of chromatin during DNA replication and DNA repair. CAF-1 is a complex of three subunits; p150, p60, and p48. This complex is localized to the nucleus of human cells. Both the composition and the biochemical activity of CAF-1 are conserved among human, yeast, and Drosophila.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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SS 1 1-13
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Isotype
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IgG1
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Purity
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Ascites
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Storage buffer
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Ascitic fluid with 0.1% sodium azide Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this p150 CAF1 antibody [SS 1 1-13] is on this datasheet. But please do contact us if you would like any reassurance! |
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References for p150 CAF1 antibody [SS 1 1-13] (ab7655)
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This product has been used in: (two most recent references)
Staresincic L et al. Coordination of dual incision and repair synthesis in human nucleotide excision repair. EMBO J 28:1111-20 (2009). WB; Human. PubMed: 19279666
Zhu Q et al. Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites. DNA Repair (Amst) 8:262-73 (2009). PubMed: 19059499
See all 9 publication references for this product.
If you publish research using ab7655 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to p150 CAF1
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p150 CAF1 antibody [SS 1 1-13] - more information
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