Overview

  • Product name
  • Description
    Mouse polyclonal to P15RS
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human P15RS protein (AAH10136.1; Q96P16-2).

  • Positive control
    • WB: human liver tissue lysate, P15RS transfected 293T cell lysate ICC/IF: HeLa cells

Properties

Applications

Our Abpromise guarantee covers the use of ab88304 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ICC/IF
  • Application notes
    ICC/IF: Use at a concentration of 10 µg/ml.
    WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 36 kDa for isoform 1 and 33 kDa for isoform 2.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
    • Sequence similarities
      Belongs to the UPF0400 (RTT103) family.
      Contains 1 CID domain.
    • Information by UniProt
    • Database links
    • Alternative names
      • C77387 antibody
      • CDKN2B-related protein antibody
      • Cyclin dependent kinase 2B inhibitor related protein antibody
      • Cyclin dependent kinase inhibitor 2B related protein (p15INK4B related protein) antibody
      • Cyclin dependent kinase inhibitor 2B related protein antibody
      • Cyclin dependent kinase inhibitor related protein antibody
      • Cyclin-dependent kinase inhibitor 2B-related protein antibody
      • FLJ10656 antibody
      • HsT3101 antibody
      • Hypothetical protein FLJ10656 antibody
      • KIAA4077 antibody
      • MGC19513 antibody
      • MGC29396 antibody
      • MGC36325 antibody
      • mKIAA4077 antibody
      • p15INK4B related protein antibody
      • p15INK4B-related protein antibody
      • Putative uncharacterized protein P15RS antibody
      • Regulation of nuclear pre mRNA domain containing 1A antibody
      • Regulation of nuclear pre-mRNA domain-containing protein 1A antibody
      • RGD1307374 antibody
      • RPR1A_HUMAN antibody
      • RPRD1A antibody
      see all

    Images

    • Anti-P15RS antibody (ab88304) at 1 µg/ml + human liver tissue lysate at 50 µg

      Predicted band size : 33 kDa
      Observed band size : 30 kDa (why is the actual band size different from the predicted?)
    • All lanes : Anti-P15RS antibody (ab88304) at 1 µg/ml

      Lane 1 : P15RS transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 50 µg per lane.


      Predicted band size : 33 kDa
      Observed band size : 32 kDa (why is the actual band size different from the predicted?)
    • ab88304, at 10 µg/ml, staining P15RS in HeLa cell by Immunofluorescence.

    References

    ab88304 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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