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Products:Cell Biology >> Cell Cycle >> Cell Cycle Inhibitors >> Ink4
Overview
Product name
Anti-p19 INK4d antibody [IMD-19]
See all p19 INK4d products (5) ...
Description
Mouse monoclonal [IMD-19] to p19 INK4d
Tested applications
WB, IHC-P, ICCmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Cow
Immunogen
Recombinant human p19INK4d.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide, 0.01% Thimerosal (merthiolate)
Constituents: 1.2% Sodium acetate, 2mg BSA
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Monoclonal
Clone number
IMD-19
Isotype
IgG1
Research areas
Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> INK4a/Arf
Epigenetics and Nuclear Signaling >> Cell cycle >> Cell Cycle Inhibitors >> Ink4
Cell Biology >> Cell Cycle >> Cell Cycle Inhibitors >> Ink4
Applications
Show applications key
Our Abpromise guarantee covers the use of ab82261 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 0.5 - 1 µg/ml.Predicted molecular weight: 17 kDa.
IHC-P: Use a concentration of 1 - 2 µg/ml.
ICC: Use at an assay dependent dilution.
Target
Relevance
Cyclins are important in regulating the cell cycle through their formation of enzymatic complexes with various cyclin dependent kinases. The activity of the cyclin D dependent kinases is controlled by inhibitors such as the INK4 family, which includes INK4a, INK4b, INK4c, and INK4d (p19 INK4d). p19 INK4d is a specific inhibitor of cdk 4 / cdk 6 and is periodically expressed during cell cycle. It is maximally induced as cells enter S phase.
Cellular localization
Cytoplasmic and Nuclear
Alternative names
- CDK inhibitor p19INK4d antibody
- CDKN 2D antibody
- CDKN2D antibody
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Database links
- Entrez Gene: 510244 Cow
- Entrez Gene: 1032 Human
- Entrez Gene: 12581 Mouse
- Entrez Gene: 494444 Rat
- Omim: 600927 Human
- SwissProt: Q29RV0 Cow
- SwissProt: P55273 Human
- SwissProt: Q60773 Mouse
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References for Anti-p19 INK4d antibody [IMD-19] (ab82261)
ab82261 has not yet been referenced specifically in any publications.
Publishing research using ab82261? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"