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Anti-p21-ARC antibody (ab37916)

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Overview

Product name

Anti-p21-ARC antibody
See all p21-ARC products (2) ...

Description

Goat polyclonal to p21-ARC

Tested applications

WBmore details

Cross reactivity

Reacts with

Mouse, Human

Predicted to work with

Rat, Cow, Xenopus laevis, Zebrafish

Immunogen

Synthetic peptide: C-RQFMNKSLSGPGQ, corresponding to C terminal amino acids 165-177 of Human p21-ARC

C-RQFMNKSLSGPGQ

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

WB: Hela, Human Brain and Mouse Brain lysates.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline. pH 7.3

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

This antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin Assembly

  • Western blot - p21-ARC antibody (ab37916)Western blot - p21-ARC antibody (ab37916) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab37916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).

Target

Relevance

p21-ARC is part of a complex implicated in the control of actin polymerization in cells. It belongs to a complex composed of ARP2, ARP3, ARPC1, ARPC2, ARPC3, ARPC4 and ARPC5, collectively known as the ARPC3 family. p21-ARC is implicated as an important regulator of growth cone translocation, especially in the CNS (Strasser et al, 2004).

Cellular localization

Cytoplasmic; cytoskeleton

Alternative names

  • Actin related protein 2/3 complex subunit 3 antibody
  • ARC21 antibody
  • ARP2/3 complex 21 kDa subunit antibody
  • ARPC3 antibody

Database links

see all

Anti-p21-ARC antibody images:

  Western blot - p21-ARC antibody (ab37916)

Western blot - p21-ARC antibody (ab37916)

Anti-p21-ARC antibody (ab37916) at 1 µg/ml + Mouse Brain lysate (RIPA buffer 35µg total protein per lane).

Predicted band size : 20 kDa


Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

References for Anti-p21-ARC antibody (ab37916)

This product has been referenced in:

  • Lippi G  et al. Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology. J Cell Biol 194:889-904 (2011). WB; Mouse.Read more (PubMed: 21930776) »

See 1 publication for this product

Publishing research using ab37916? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"