Overview

  • Product nameAnti-p23 antibody
    See all p23 primary antibodies
  • Description
    Rabbit polyclonal to p23
  • Specificityab74111 detects endogenous levels of total p23 protein.
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthesized non phosphopeptide derived from human p23 around the phosphorylation site of serine 113 (D-D-SP-D-E).

  • Positive control
    • WB: extracts from NIH/3T3 cells, treated with EGF (200ng/ml, 30mins). IHC-P: human lung carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab74111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 19 kDa.
ELISA 1/5000.
IHC-P 1/50 - 1/100.

Target

  • FunctionMolecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
  • PathwayLipid metabolism; prostaglandin biosynthesis.
  • Sequence similaritiesBelongs to the p23/wos2 family.
    Contains 1 CS domain.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Co chaperone p23 antibody
    • cPGES antibody
    • Cytosolic prostaglandin E synthase antibody
    • Cytosolic prostaglandin E2 synthase antibody
    • Hsp90 co chaperone antibody
    • Hsp90 co-chaperone antibody
    • P23 antibody
    • Progesterone receptor complex antibody
    • Progesterone receptor complex p23 antibody
    • Prostaglandin E synthase 3 (cytosolic) antibody
    • Prostaglandin E synthase 3 antibody
    • PTGES 3 antibody
    • PTGES3 antibody
    • Sid 3177 antibody
    • TEBP antibody
    • TEBP_HUMAN antibody
    • Telomerase binding protein p23 antibody
    • Telomerase-binding protein p23 antibody
    • Unactive progesterone receptor 23 kD antibody
    see all

Anti-p23 antibody images

  • All lanes : Anti-p23 antibody (ab74111) at 1/500 dilution

    Lane 1 : Extracts from NIH/3T3 cells treated with EGF (200ng/ml, 30mins)
    Lane 2 : Extracts from NIH/3T3 cells treated with EGF (200ng/ml, 30mins), plus peptide at 10 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 19 kDa
    Observed band size : 23 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 41 kDa. We are unsure as to the identity of these extra bands.
  • ab74111, at a 1/50 dilution, staining p23 in paraffin embedded human lung carcinoma tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the immunising peptide.

References for Anti-p23 antibody (ab74111)

ab74111 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"