Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab10248 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/1000.
ICC 1/1000.
IHC-P Use at an assay dependent concentration. PubMed: 21969132

Target

  • FunctionLigand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death.
  • Sequence similaritiesBelongs to the P2X receptor family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ATP receptor antibody
    • H.sapiens mRNA for ATP receptor antibody
    • P2 RX1 antibody
    • P2rx1 antibody
    • P2RX1 protein antibody
    • P2RX1_HUMAN antibody
    • P2X purinoceptor 1 antibody
    • P2X receptor subunit 1 antibody
    • P2X1 antibody
    • P2X1 receptor antibody
    • Purinergic receptor antibody
    • Purinergic receptor P2X ligand gated ion channel 1 antibody
    • Purinergic receptor P2X1 antibody
    see all

Anti-P2X1 antibody images

  • ab10248, at a dilution of 1/1000, staining P2X1 in rat vas deferens smooth muscle cells by Immunohistochemistry (PFA perfusion fixed frozen sections).

References for Anti-P2X1 antibody (ab10248)

This product has been referenced in:
  • Neuhaus J  et al. Individual receptor profiling as a novel tool to support diagnosis of bladder pain syndrome/interstitial cystitis (BPS/IC). World J Urol : (2011). IHC-P ; Human . Read more (PubMed: 21969132) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"