The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 21969132
FunctionLigand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death.
Sequence similaritiesBelongs to the P2X receptor family.
ab10248, at a dilution of 1/1000, staining P2X1 in rat vas deferens smooth muscle cells by Immunohistochemistry (PFA perfusion fixed frozen sections).
References for Anti-P2X1 antibody (ab10248)
This product has been referenced in:
Neuhaus J et al. Individual receptor profiling as a novel tool to support diagnosis of bladder pain syndrome/interstitial cystitis (BPS/IC). World J Urol : (2011).
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