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Overview

  • Product namep400 peptideSee all p400 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 200 - 300 of Human p400. (Note: the amino acid sequence is proprietary). 
  • Protein length3160 amino acids

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab13753 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Blocking
  • Application notesBL: Use at an assay dependent dilution.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        CAG repeat protein 32CAGH 32CAGH32
        DKFZP434I225Domino homologE1A binding protein p400E1A-binding protein p400EP 400EP400EP400_HUMANFLJ42018FLJ45115hDominoKIAA1498KIAA1818p400 kDa SWI2/SNF2 related proteinp400 kDa SWI2/SNF2-related proteinP400 SWI2/SNF2 related proteinP400 SWI2/SNF2-related proteinTNRC 12TNRC12Trinucleotide repeat containing 12Trinucleotide repeat containing gene 12 proteinTrinucleotide repeat-containing gene 12 protein
      see all
  • FunctionComponent of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.
  • Tissue specificityUbiquitously expressed.
  • Sequence similaritiesBelongs to the SNF2/RAD54 helicase family. SWR1 subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
    Contains 1 HSA domain.
    Contains 1 Myb-like domain.
  • Cellular localizationNucleus.

    • Target information above from: UniProt accession Q96L91 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for p400 peptide (ab13753)

    ab13753 has not yet been referenced specifically in any publications.

    Publishing research using ab13753 ? Please let us know so that we can cite the reference in this datasheet

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