Anti-Centaurin alpha 1 antibody [P421] (ab10168)

Overview

• Product nameAnti-Centaurin alpha 1 antibody [P421]See all Centaurin alpha 1 primary antibodies ...
• Description
  Mouse monoclonal [P421] to Centaurin alpha 1
• Tested applicationsWB, ELISA more details
• Species reactivity
  Reacts with: Pig
  
• Immunogen

  Recombinant full length protein (Pig).

• General notesConcentration varies from lot to lot and can be provided on request.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.1% Sodium Azide
  Constituents: PBS, pH 7.4
• Concentration information loading...
• PurityProtein A purified
• Purification notesPurity tested by electrophoresis.
• Clonality Monoclonal
• Clone numberP421
• MyelomaSp2/0
• IsotypeIgG1
• Research Areas
  • Signal Transduction
  • Second Messenger
  • Nucleotide Messenger
  • GTP

  • Signal Transduction
  • Signaling Pathway
  • Lipid Signaling
  • Other

  • Signal Transduction
  • Adapters
  • Cytoplasmic

  • Neuroscience
  • Neurology process
  • Neural Signal Transduction

Applications

Target

• RelevanceThe centaurin alpha 1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2 adrenoceptor internalization and negatively regulates ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP.
• Cellular localizationCytoplasmic, Nuclear and Plasma membrane
• Database links
  • Entrez Gene: 397453 Pig
  • SwissProt: O02780 Pig

• Alternative names
  ArfGAP with dual PH domains 1 antibodyCENTA 1 antibodyCENTA1 antibody

  Centaurin alpha antibodycentaurin antibodyGCS1L antibodyInositol 1345 Tetrakisphosphate Receptor 42kDa antibodyp42IP4 antibodyPutative MAPK activating protein PM25 antibody

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