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Product Name
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Centaurin alpha 1 antibody [P421]
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See all Centaurin alpha 1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [P421] to Centaurin alpha 1
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Immunogen
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Recombinant full length protein (Pig).
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Reacts with
(species key)
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Pig
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 42 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Signal Transduction >> Second Messenger >> Nucleotide Messenger >> GTP
Signal Transduction >> Signaling Pathway >> Lipid Signaling >> Other
Signal Transduction >> Adapters >> Cytoplasmic
Neuroscience >> Neurology process >> Neural Signal Transduction
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Relevance
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The centaurin alpha 1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2 adrenoceptor internalization and negatively regulates ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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P421
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Myeloma
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Sp2/0
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Isotype
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IgG1
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Purity tested by electrophoresis.
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Form
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Liquid
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Concentration
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2.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Notes
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Concentration varies from lot to lot and can be provided on request.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Centaurin alpha 1 antibody [P421] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Centaurin alpha 1
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