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Products:Neuroscience >> Neurology process >> Neural Signal Transduction
Overview
Product name
Anti-Centaurin alpha 1 antibody [P421]
See all Centaurin alpha 1 products (3) ...
Description
Mouse monoclonal [P421] to Centaurin alpha 1
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Pig
Immunogen
Recombinant full length protein (Pig).
General notes
Concentration varies from lot to lot and can be provided on request.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein A purified
Purification notes
Purity tested by electrophoresis.
Clonality
Monoclonal
Clone number
P421
Myeloma
Sp2/0
Isotype
IgG1
Research areas
Signal Transduction >> Second Messenger >> Nucleotide Messenger >> GTP
Signal Transduction >> Signaling Pathway >> Lipid Signaling >> Other
Signal Transduction >> Adapters >> Cytoplasmic
Neuroscience >> Neurology process >> Neural Signal Transduction
Applications
Show applications key
Our Abpromise guarantee covers the use of ab10168 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 42 kDa.
ELISA: Use at an assay dependent dilution.
Target
Relevance
The centaurin alpha 1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), centaurin alpha 1 is able to switch off ARF6 and inhibit its ability to mediate beta 2 adrenoceptor internalization and negatively regulates ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP.
Cellular localization
Cytoplasmic, Nuclear and Plasma membrane
Alternative names
- ArfGAP with dual PH domains 1 antibody
- CENTA 1 antibody
- CENTA1 antibody
see all
Database links
References for Anti-Centaurin alpha 1 antibody [P421] (ab10168)
ab10168 has not yet been referenced specifically in any publications.
Publishing research using ab10168? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"