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ab26 has been referenced in 75 publications.

  • Singh A  et al. Podophyllotoxin and Rutin Modulates Ionizing Radiation-Induced Oxidative Stress and Apoptotic Cell Death in Mice Bone Marrow and Spleen. Front Immunol 8:183 (2017). PubMed: 28289414
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  • Kim SB  et al. Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses. Oncogene 35:3365-75 (2016). WB ; Mouse . PubMed: 26477319
  • Zeng H  et al. Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid-Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration. Drug Metab Dispos 44:337-42 (2016). WB ; Mouse . PubMed: 26658429
  • Zhuang Y  et al. Mitochondrial p53 Contributes to Reovirus-Induced Neuronal Apoptosis and Central Nervous System Injury in a Mouse Model of Viral Encephalitis. J Virol 90:7684-91 (2016). IP ; Mouse . PubMed: 27307572
  • Walton J  et al. CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma. Cancer Res 76:6118-6129 (2016). PubMed: 27530326
  • Cabral VD  et al. p14 expression differences in ovarian benign, borderline and malignant epithelial tumors. J Ovarian Res 9:69 (2016). IHC ; Human . PubMed: 27770808
  • Suzuki I  et al. 4-Methylthio-3-butenyl isothiocyanate (raphasatin) exerts chemopreventive effects against esophageal carcinogenesis in rats. J Toxicol Pathol 29:237-246 (2016). IHC-P ; Rat . PubMed: 27821908
  • Bauer MR  et al. 2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells. Proc Natl Acad Sci U S A 113:E5271-80 (2016). PubMed: 27551077
  • Hu Z  et al. Enhancement of anti-tumor effects of 5-fluorouracil on hepatocellular carcinoma by low-intensity ultrasound. J Exp Clin Cancer Res 35:71 (2016). Human . PubMed: 27102814
  • Sun J  et al. Dendrobium candidum inhibits MCF-7 cells proliferation by inducing cell cycle arrest at G2/M phase and regulating key biomarkers. Onco Targets Ther 9:21-30 (2016). WB ; Human . PubMed: 26730200
  • Chen CC  et al. The matricellular protein CCN1 suppresses hepatocarcinogenesis by inhibiting compensatory proliferation. Oncogene 35:1314-23 (2016). IHC-P ; Human . PubMed: 26028023
  • Ren M  et al. A biofidelic 3D culture model to study the development of brain cellular systems. Sci Rep 6:24953 (2016). ICC/IF ; Rat . PubMed: 27112667
  • Garcia PV  et al. Increased toll-like receptors and p53 levels regulate apoptosis and angiogenesis in non-muscle invasive bladder cancer: mechanism of action of P-MAPA biological response modifier. BMC Cancer 16:422 (2016). WB . PubMed: 27389279
  • Cheng CY  et al. Electroacupuncture at different frequencies (5Hz and 25Hz) ameliorates cerebral ischemia-reperfusion injury in rats: possible involvement of p38 MAPK-mediated anti-apoptotic signaling pathways. BMC Complement Altern Med 15:241 (2015). WB ; Rat . PubMed: 26187498
  • Augello MA  et al. Consequence of the tumor-associated conversion to cyclin D1b. EMBO Mol Med 7:628-47 (2015). PubMed: 25787974
  • Kurkalang S  et al. Precocious anaphase and expression of Securin and p53 genes as candidate biomarkers for the early detection in areca nut-induced carcinogenesis. Mutagenesis 30:381-9 (2015). PubMed: 25480871
  • Petti E  et al. Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice. Cell Cycle 14:1438-46 (2015). WB . PubMed: 25789788
  • Zhang W  et al. PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis. Oncotarget 6:9420-33 (2015). IP ; Mouse . PubMed: 25826083
  • De Cesare M  et al. Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin. Oncotarget 6:13119-32 (2015). Human . PubMed: 25948791
  • Quijada P  et al. Nuclear Calcium/Calmodulin-dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage Commitment. J Biol Chem 290:25411-26 (2015). WB ; Mouse . PubMed: 26324717
  • Li P  et al. Methylation of Werner syndrome protein is associated with the occurrence and development of invasive meningioma via the regulation of Myc and p53 expression. Exp Ther Med 10:498-502 (2015). Human . PubMed: 26622343
  • Nadeau MÈ  et al. Pharmacological targeting of valosin containing protein (VCP) induces DNA damage and selectively kills canine lymphoma cells. BMC Cancer 15:479 (2015). WB ; Dog . PubMed: 26104798
  • Ho DH  et al. Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression. Mol Brain 8:54 (2015). IP ; Mouse . PubMed: 26384650
  • Xu B  et al. Oridonin inhibits BxPC-3 cell growth through cell apoptosis. Acta Biochim Biophys Sin (Shanghai) 47:164-73 (2015). WB ; Human . PubMed: 25651847
  • Ikitimur-Armutak EI  et al. Anticancer effect of a novel palladium-saccharinate complex of terpyridine by inducing apoptosis on Ehrlich ascites carcinoma (EAC) in Balb-C mice. Anticancer Res 35:1491-7 (2015). Mouse . PubMed: 25750302
  • Chen R  et al. Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs. J Biol Chem 290:30813-29 (2015). WB ; Mouse . PubMed: 26518879
  • Nishimatsu H  et al. Senescent Cells Impair Erectile Function through Induction of Endothelial Dysfunction and Nerve Injury in Mice. PLoS One 10:e0124129 (2015). WB . PubMed: 25894557
  • Huang EY  et al. Amifostine alleviates radiation-induced lethal small bowel damage via promotion of 14-3-3s-mediated nuclear p53 accumulation. Oncotarget 5:9756-69 (2014). ICC/IF ; Human . PubMed: 25230151
  • Seo H  et al. Antioxidant and antiapoptotic effects of pine needle powder ingestion and endurance training in high cholesterol-fed rats. J Exerc Nutrition Biochem 18:301-9 (2014). WB ; Mouse . PubMed: 25566467
  • Koo SM  et al. p53 Expression in a Malignant Mesothelioma Patient during Seven-Year Follow-up. Tuberc Respir Dis (Seoul) 76:284-8 (2014). IHC-P ; Human . PubMed: 25024722
  • Gazzaniga FS & Blackburn EH An antiapoptotic role for telomerase RNA in human immune cells independent of telomere integrity or telomerase enzymatic activity. Blood 124:3675-84 (2014). WB ; Human . PubMed: 25320237
  • Toko H  et al. Differential regulation of cellular senescence and differentiation by prolyl isomerase Pin1 in cardiac progenitor cells. J Biol Chem 289:5348-56 (2014). Mouse . PubMed: 24375406
  • Takemura N  et al. Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome. Nat Commun 5:3492 (2014). IHC-P ; Mouse . PubMed: 24637670
  • Starha P  et al. Pharmacological and molecular effects of platinum(II) complexes involving 7-azaindole derivatives. PLoS One 9:e90341 (2014). WB, IHC-P ; Mouse . PubMed: 24603594
  • Munne PM  et al. TP53 supports basal-like differentiation of mammary epithelial cells by preventing translocation of deltaNp63 into nucleoli. Sci Rep 4:4663 (2014). ICC/IF ; Human . PubMed: 24722541
  • Pei L  et al. DAPK1-p53 interaction converges necrotic and apoptotic pathways of ischemic neuronal death. J Neurosci 34:6546-56 (2014). PubMed: 24806680
  • Larive RM  et al. Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease. Nat Commun 5:3881 (2014). PubMed: 24826867
  • Mustafa Rizvi SH  et al. Aluminium induced endoplasmic reticulum stress mediated cell death in SH-SY5Y neuroblastoma cell line is independent of p53. PLoS One 9:e98409 (2014). WB ; Human . PubMed: 24878590
  • Valle C  et al. Tissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways. Cell Death Dis 5:e1296 (2014). PubMed: 24946089
  • Martin L  et al. Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutations. Cancer Res 74:3104-13 (2014). WB . PubMed: 24662918
  • Ubil E  et al. Mesenchymal-endothelial transition contributes to cardiac neovascularization. Nature 514:585-90 (2014). Histology, Immunomicroscopy, IHC, Alexa Fluor® 680 ; Mouse . PubMed: 25317562
  • Kurkalang S  et al. Induction of chromosome instability and stomach cancer by altering the expression pattern of mitotic checkpoint genes in mice exposed to areca-nut. BMC Cancer 13:315 (2013). WB ; Mouse . PubMed: 23805780
  • Riggs JW  et al. Induced pluripotency and oncogenic transformation are related processes. Stem Cells Dev 22:37-50 (2013). WB ; Mouse . PubMed: 22998387
  • Crowder SW  et al. Passage-dependent cancerous transformation of human mesenchymal stem cells under carcinogenic hypoxia. FASEB J 27:2788-98 (2013). Human . PubMed: 23568779
  • Wang X  et al. Microcystin (-LR) induced testicular cell apoptosis via up-regulating apoptosis-related genes in vivo. Food Chem Toxicol 60:309-17 (2013). PubMed: 23891578
  • Liu X  et al. Small molecule induced reactivation of mutant p53 in cancer cells. Nucleic Acids Res 41:6034-44 (2013). PubMed: 23630318
  • Wallace MD  et al. Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress. Oncogene N/A:N/A (2013). PubMed: 23975433
  • Jørgensen M  et al. Extracellular Vesicle (EV) Array: microarray capturing of exosomes and other extracellular vesicles for multiplexed phenotyping. J Extracell Vesicles 2:N/A (2013). Dot blot ; Human . PubMed: 24009888
  • Fávaro WJ  et al. Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer. Infect Agent Cancer 7:14 (2012). WB ; Rat . PubMed: 22709446
  • Khalil HS  et al. Pharmacological inhibition of ATM by KU55933 stimulates ATM transcription. Exp Biol Med (Maywood) 237:622-34 (2012). PubMed: 22728709
  • Surget S  et al. Cell death via DR5, but not DR4, is regulated by p53 in myeloma cells. Cancer Res 72:4562-73 (2012). IP ; Human . PubMed: 22738917
  • Xiao F  et al. WITHDRAWN: Hexavalent chromium induces premature senescence through reactive oxygen species-mediated p53 pathway in L-02 hepatocytes. Biochem Biophys Res Commun N/A:N/A (2012). PubMed: 22521640
  • Wan YW  et al. A smoking-associated 7-gene signature for lung cancer diagnosis and prognosis. Int J Oncol 41:1387-96 (2012). WB ; Human . PubMed: 22825454
  • Heby-Henricson K  et al. Loss of Trp53 promotes medulloblastoma development but not skin tumorigenesis in Sufu heterozygous mutant mice. Mol Carcinog 51:754-60 (2012). IHC-P ; Mouse . PubMed: 21882258
  • Farioli-Vecchioli S  et al. Btg1 is Required to Maintain the Pool of Stem and Progenitor Cells of the Dentate Gyrus and Subventricular Zone. Front Neurosci 6:124 (2012). IHC-Fr ; Mouse . PubMed: 22969701
  • Gu BW  et al. Accelerated hematopoietic stem cell aging in a mouse model of dyskeratosis congenita responds to antioxidant treatment. Aging Cell 10:338-48 (2011). Mouse . PubMed: 21241452
  • Shen W  et al. Female infertility in PDE3A (-/-) mice: Polo-like kinase 1 (Plk1) may be a target of Protein Kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A (-/- ) mice. Cell Cycle 9:4720-34 (2010). WB ; Mouse . PubMed: 21099356
  • Guillen-Ahlers H  et al. Fas/CD95 Deficiency in Apc Mice Increases Intestinal Tumor Burden. PLoS One 5:e9070 (2010). IHC-P ; Mouse . PubMed: 20140201
  • Roa W  et al. Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycle. Nanotechnology 20:375101 (2009). PubMed: 19706948
  • Pan D  et al. SnoN functions as a tumour suppressor by inducing premature senescence. EMBO J : (2009). WB, ICC/IF ; Mouse . PubMed: 19745809
  • Yeo J  et al. Label-free electrochemical detection of the p53 core domain protein on its antibody immobilized electrode. Anal Chem 81:4770-7 (2009). WB . PubMed: 19435284
  • Izadpanah R  et al. Long-term in vitro expansion alters the biology of adult mesenchymal stem cells. Cancer Res 68:4229-38 (2008). WB ; Human . PubMed: 18519682
  • Gu BW  et al. A pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in mice. Proc Natl Acad Sci U S A 105:10173-8 (2008). WB ; Mouse . PubMed: 18626023
  • Blickwedehl J  et al. Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability. Proc Natl Acad Sci U S A 105:16165-70 (2008). PubMed: 18845680
  • Hudson CD  et al. Brn-3a/POU4F1 interacts with and differentially affects p73-mediated transcription. Cell Death Differ 15:1266-78 (2008). WB . PubMed: 18421303
  • Blanco D  et al. Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16 and activation of the DNA damage response pathway. Neoplasia 9:840-52 (2007). IHC-P ; Rat . PubMed: 17971904
  • Broom WJ  et al. Inhibition of SOD1 expression by mitomycin C is a non-specific consequence of cellular toxicity. Neurosci Lett 393:184-8 (2006). PubMed: 16242241
  • Cheng W  et al. DeltaNp63 plays an anti-apoptotic role in ventral bladder development. Development 133:4783-92 (2006). PubMed: 17079275
  • Xia F & Altieri DC Mitosis-independent survivin gene expression in vivo and regulation by p53. Cancer Res 66:3392-5 (2006). WB ; Human . PubMed: 16585159
  • Hudson CD  et al. Coexpression of Brn-3a POU protein with p53 in a population of neuronal progenitor cells is associated with differentiation and protection against apoptosis. J Neurosci Res 78:803-14 (2004). PubMed: 15532030
  • Krones-Herzig A  et al. Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence. Proc Natl Acad Sci U S A 100:3233-8 (2003). IP ; Mouse . PubMed: 12629205
  • Wang PL  et al. The 'wildtype' conformation of p53: epitope mapping using hybrid proteins. Oncogene 20:2318-24 (2001). PubMed: 11402327
  • Stephen CW & Lane DP Mutant conformation of p53. Precise epitope mapping using a filamentous phage epitope library. J Mol Biol 225:577-83 (1992). PubMed: 1376364
  • Gannon JV  et al. Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J 9:1595-602 (1990). PubMed: 1691710

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