Anti-p63 Protein + HMW Cytokeratin antibody [4A4, 34] (ab58514)

Overview

  • Product nameAnti-p63 Protein + HMW Cytokeratin antibody [4A4, 34]
  • Description
    Mouse monoclonal [4A4, 34] to p63 Protein + HMW Cytokeratin
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human p63 protein (aa 1-205) and cytokeratin extract of human stratum corneum

  • Positive control
    • Normal prostate tissue or skin
  • General notesab58514 isotypes: IgG2a + IgG1

Properties

Applications

Our Abpromise guarantee covers the use of ab58514 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: ready to use, 100 µl working solution / test. Antigen retrieval requires unmasking, TEC buffer (Tris/EDTA/Citrate) pH 8 in a pressure cooker at 100°C 20-40 minutes


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceThe p63 and high molecular weight cytokeratin cocktail is a marker for basal cells. The p63 protein, a homologue of the tumour-suppressor p53, is highly expressed in the nuclei of basal or progenitor layer of many epithelial tissues. p63 is detected in prostate basal cells in normal prostate glands and PIN. Other markers for basal cells are high molecular cytokeratins (CK 1, 5, 10 and 14). The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells.
    • Cellular localizationCytoplasmic and Nuclear
    • Database links
    • Alternative names
      • CK13 antibody
      • CK14 antibody
      • CK15 antibody
      • CK16 antibody
      • Cytokeratin 13 antibody
      • Cytokeratin 14 antibody
      • Cytokeratin 15 antibody
      • Cytokeratin 16 antibody
      • K13 antibody
      • K14 antibody
      • K15 antibody
      • K16 antibody
      • Keratin 13 antibody
      • Keratin 14 antibody
      • Keratin 15 antibody
      • Keratin 16 antibody
      • KRT13 antibody
      • KRT14 antibody
      • KRT15 antibody
      • KRT16 antibody
      • p40 antibody
      • p51 antibody
      • p63 antibody
      • p73L antibody
      • TP63 antibody
      • Tumor protein 63 antibody
      • Tumor protein p73-like antibody
      see all

    References for Anti-p63 Protein + HMW Cytokeratin antibody [4A4, 34] (ab58514)

    ab58514 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"