Overview

  • Product name
  • Description
    Goat polyclonal to p66 beta
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from Human p66 beta.

  • Positive control
    • Human Adrenal and Human Spleen tissues

Properties

Applications

Our Abpromise guarantee covers the use of ab111248 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Has transcriptional repressor activity. Targets MBD3 to discrete loci in the nucleus.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Contains 1 GATA-type zinc finger.
  • Domain
    CR1 is required for interaction with MBD3 and transcription repression.
    CR2 is required for localization to discrete loci in the nucleus.
  • Cellular localization
    Nucleus. Nuclear, in discrete foci.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ37346 antibody
    • GATA zinc finger domain containing 2B antibody
    • GATA zinc finger domain containing protein 2B antibody
    • GATA zinc finger domain-containing protein 2B antibody
    • GATAD2B antibody
    • KIAA1150 antibody
    • MGC138257 antibody
    • MGC138285 antibody
    • mKIAA1150 antibody
    • p66/p68 antibody
    • P66B_HUMAN antibody
    • P66beta antibody
    • RGD1308533 antibody
    • transcription repressor p66 beta component of the MeCP1 complex antibody
    • Transcriptional repressor p66 beta antibody
    • Transcriptional repressor p66-beta antibody
    see all

Images

  • Formalin-Fixed, Paraffin-Embedded Human Adrenal tissue stained using ab111248 at a concentration of 3.75 µg/ml.
  • Formalin-Fixed, Paraffin-Embedded Human Spleen tissue stained using ab111248 at a concentration of 3.75 µg/ml.

References

ab111248 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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