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Rabbit polyclonal to P70 S6 Kinase beta (phospho S371)
ab60947 detects endogenous levels of P70 S6 Kinase beta only when phosphorylated at serine 371.
Predicted to work with:
Synthetic phosphopeptide derived from human P70 S6 Kinase beta around the phosphorylation site of serine 371 (V-D-S
Human breast carcinoma tissue.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg 2+ and Ca 2+), 150mM Sodium chloride, pH 7.4
Concentration information loading...
Immunogen affinity purified
ab60947 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 23874880
1/50 - 1/100.
1/50 - 1/100.
Phosphorylates specifically ribosomal protein S6.
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
70 kDa ribosomal protein S6 kinase 2 antibody
EC 22.214.171.124 antibody
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