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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg 2+ and Ca 2+), 150mM Sodium chloride, pH 7.4
Concentration information loading...
Purity Immunogen affinity purified
Purification notes ab60947 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 23874880
1/50 - 1/100.
1/50 - 1/100.
Function Phosphorylates specifically ribosomal protein S6.
Sequence similarities Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain.
Post-translational modifications Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
70 kDa ribosomal protein S6 kinase 2 antibody
EC 18.104.22.168 antibody
Anti-P70 S6 Kinase beta (phospho S371) antibody images
References for Anti-P70 S6 Kinase beta (phospho S371) antibody (ab60947)
This product has been referenced in:
et al. Targeting mTOR to overcome epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small cell lung cancer cells. PLoS One 8:e69104 (2013).
Read more (PubMed: 23874880) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"