Recombinant
RabMAb

Anti-P70 S6 Kinase beta (phospho S371) antibody [EPR2132] (ab109393)

Overview

  • Product name
    Anti-P70 S6 Kinase beta (phospho S371) antibody [EPR2132]
    See all P70 S6 Kinase beta primary antibodies
  • Description
    Rabbit monoclonal [EPR2132] to P70 S6 Kinase beta (phospho S371)
  • Specificity
    This antibody only detects p70 S6 Kinase phosphorylated at serine 371.
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A phospho specific peptide corresponding to residues surrounding serine 371 of Human p70 S6 Kinase.

  • Positive control
    • 293T cell lysate treated with Alkaline Phosphatase (AP).
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab109393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 53 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function
      Phosphorylates specifically ribosomal protein S6.
    • Sequence similarities
      Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Information by UniProt
    • Database links
    • Alternative names
      • 70 kDa ribosomal protein S6 kinase 2 antibody
      • EC 2.7.11.1 antibody
      • KS6B2_HUMAN antibody
      • p70 beta antibody
      • p70 ribosomal S6 kinase beta antibody
      • p70 S6 kinase beta antibody
      • p70 S6K-beta antibody
      • p70 S6KB antibody
      • p70 S6Kbeta antibody
      • p70(S6K) beta antibody
      • p70-beta antibody
      • p70-S6K 2 antibody
      • P70S6K2 antibody
      • p70S6Kb antibody
      • Ribosomal protein S6 kinase 70kDa, polypeptide 2 antibody
      • Ribosomal protein S6 kinase B2 antibody
      • Ribosomal protein S6 kinase beta 2 antibody
      • Ribosomal protein S6 kinase beta-2 antibody
      • Rps6kb2 antibody
      • S6 kinase related kinase antibody
      • S6 kinase-related kinase antibody
      • S6K beta 2 antibody
      • S6K beta antibody
      • S6K-beta antibody
      • S6K-beta-2 antibody
      • S6K2 antibody
      • Serine/threonine protein kinase 14 beta antibody
      • Serine/threonine-protein kinase 14B antibody
      • SRK antibody
      • STK14B antibody
      see all

    Images

    • All lanes : Anti-P70 S6 Kinase beta (phospho S371) antibody [EPR2132] (ab109393) at 1/1000 dilution

      Lane 1 : 293T cell lysate, untreated
      Lane 2 : 293T cell lysate, treated with Alkaline Phosphatase (AP)

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 53 kDa

    References

    This product has been referenced in:
    • Mei W  et al. Gambogenic acid kills lung cancer cells through aberrant autophagy. PLoS One 9:e83604 (2014). WB ; Human . Read more (PubMed: 24427275) »
    • Xu R  et al. The protease Omi regulates mitochondrial biogenesis through the GSK3ß/PGC-1a pathway. Cell Death Dis 5:e1373 (2014). WB ; Mouse . Read more (PubMed: 25118933) »

    See all 4 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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