p75 NGF Receptor protein (Active) (ab83678)
Constituents: 10% Trehalose, 1% Human serum albumin, PBS
Our Abpromise guarantee covers the use of ab83678 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Functional Studies||FuncS: Use at an assay dependent dilution.|
|SDS-PAGE||SDS-PAGE: Use at an assay dependent dilution. This chimera migrates as a broad band between 75 and 100 kDa in SDS-PAGE due to post-translation modifications, in particular glycosylation. This compares with unmodified chimera that has a predicted molecular mass of 50.8 kDa. This chimera separates into a number of isoforms with a pI between 4.0 and 6.0 in 2D PAGE due to post-translational modifications, in particular glycosylation. This compares with the unmodified chimera that has a predicted pI of 4.89.|
- CD271CD271 antigenGp80 LNGFR
- Gp80-LNGFRLow affinity nerve growth factor receptorLow affinity neurotrophin receptor p75NTRLow affinity neurotrophin receptor p75NTRLow-affinity nerve growth factor receptorNerve growth factor receptorNerve growth factor receptor TNFR superfamily member 16NGF receptorNGF receptorNGFRp75 ICDp75 ICDp75 Neurotrophin receptorp75 NTRp75(NTR)p75NTRTNFR Superfamily Member 16TNFRSF16TNR16_HUMANTumor necrosis factor receptor superfamily member 16
Contains 4 TNFR-Cys repeats.
The extracellular domain is responsible for interaction with NTRK1.
modificationsN- and O-glycosylated.
O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc.
Phosphorylated on serine residues.
References for p75 NGF Receptor protein (Active) (ab83678)
ab83678 has not yet been referenced specifically in any publications.