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Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer pH: 7.4 Preservative: 0.02% Sodium azide Constituent: PBS
Concentration information loading...
Purity IgG fraction
Clone number 5C4B9
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 5 µg/ml. Detects a band of approximately 74 kDa (predicted molecular weight: 75 kDa).
Function Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.
Sequence similarities Contains 1 death domain. Contains 4 TNFR-Cys repeats.
Domain Death domain is responsible for interaction with RANBP9. The extracellular domain is responsible for interaction with NTRK1.
Post-translational modifications N- and O-glycosylated. O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc. Phosphorylated on serine residues.
Cellular localization Membrane.
Information by UniProt
CD271 antigen antibody
Gp80 LNGFR antibody
Anti-p75 NGF Receptor antibody [5C4B9] images
Western blot - p75 NGF Receptor antibody [5C4B9] (ab86768)
All lanes : Anti-p75 NGF Receptor antibody [5C4B9] (ab86768) at 5 µg/ml Lane 1 : Brain (Mouse) Tissue Lysate Lane 2 : Spinal Cord (Mouse) Tissue Lysate Lane 3 : Heart (Mouse) Tissue Lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Mouse IgG H&L (HRP) preadsorbed ( ab97040) at 1/5000 dilution Developed using the ECL technique Performed under reducing conditions. Predicted band size : 75 kDa Observed band size : 74 kDa ( why is the actual band size different from the predicted?) Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands. Exposure time : 16 minutes
References for Anti-p75 NGF Receptor antibody [5C4B9] (ab86768)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"