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Anti-p90 Autoantigen antibody [2G10] - Carboxyterminal end (ab61863)

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Overview

  • Product nameAnti-p90 Autoantigen antibody [2G10] - Carboxyterminal endSee all p90 Autoantigen primary antibodies ...
  • Description
    Mouse monoclonal [2G10] to p90 Autoantigen - Carboxyterminal end
  • Tested applicationsWB, ICC/IF more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A C-terminal portion of the human p90 Autoantigen.

  • EpitopeA 300 amino acid portion of the C-terminus region of p90 Autoantigen.
  • Positive controlHeLa whole cell extract.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: Tris glycine, 150mM Sodium chloride
  • Concentration information loading...
  • PurityProtein G purified
  • Clonality Monoclonal
  • Clone number2G10
  • IsotypeIgG2b
  • Light chain typekappa
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab61863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).
ICC/IF ICC/IF: Use at an assay dependent dilution.

Target

  • FunctionOncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.
  • Tissue specificityExpressed at low levels in most of the tissues. Overexpressed in head-and-neck squamous cell carcinomas (HNSCC). Present in liver cancer cells (at protein level).
  • Cellular localizationMembrane. Cytoplasm. Slightly concentrates in the perinuclear region.

    • Target information above from: UniProt accession Q8TCG1 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        Cancerous inhibitor of PP2A antibodyCancerous Inhibitor of Protein Phosphatase 2A antibodyCIP2A antibody
        CIP2A_HUMAN antibodyFLJ12850 antibodyKiaa1524 antibodyMGC163436 antibodyp90 antibodyp90 autoantigen antibodyProtein CIP2A antibody
      see all

    Anti-p90 Autoantigen antibody [2G10] - Carboxyterminal end images

    • Western blot - p90 Autoantigen antibody [2G10] (ab61863)
      Western blot - p90 Autoantigen antibody [2G10] (ab61863)
      Anti-p90 Autoantigen antibody [2G10] - Carboxyterminal end (ab61863) at 0.5 µg/ml + HeLa whole cell lysate

      Predicted band size : 102 kDa
      Observed band size : 102 kDa

    References for Anti-p90 Autoantigen antibody [2G10] - Carboxyterminal end (ab61863)

    ab61863 has not yet been referenced specifically in any publications.

    Publishing research using ab61863 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"