• Product name
  • Description
    Rabbit polyclonal to PABPC4
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide: AELGAKAKEF TNVYIKNFGE EVDDESLKEL FSQFGKTLSV KVMRDPNGKS, corresponding to a region within amino acids 181-230 of Human PABPC4.

  • Positive control
    • Human kidney tissue. HepG2 cell lysate.



Our Abpromise guarantee covers the use of ab66897 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.


  • Function
    Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.
  • Tissue specificity
    Expressed at low levels in resting normal T cells; following T-cell activation, however, mRNA levels are rapidly up-regulated.
  • Sequence similarities
    Belongs to the polyadenylate-binding protein type-1 family.
    Contains 1 PABC domain.
    Contains 4 RRM (RNA recognition motif) domains.
  • Post-translational
    Arg-518 is dimethylated, probably to asymmetric dimethylarginine.
  • Cellular localization
    Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activated platelet protein 1 antibody
    • Activated-platelet protein 1 antibody
    • APP 1 antibody
    • APP-1 antibody
    • APP1 antibody
    • FLJ43938 antibody
    • Inducible poly(A) binding protein antibody
    • Inducible poly(A)-binding protein antibody
    • iPABP antibody
    • IPABP4 antibody
    • PABP 4 antibody
    • PABP-4 antibody
    • PABP4 antibody
    • PABP4_HUMAN antibody
    • PABPC 4 antibody
    • PABPC4 antibody
    • Poly A binding protein cytoplasmic 4 antibody
    • Poly(A) binding protein 4 antibody
    • Poly(A) binding protein cytoplasmic 4 (inducible form) antibody
    • Poly(A) binding protein cytoplasmic 4 antibody
    • Poly(A)-binding protein 4 antibody
    • Polyadenylate binding protein 4 antibody
    • Polyadenylate-binding protein 4 antibody
    • Polyadenylate-binding protein, cytoplasmic, 4 antibody
    • Polyadenylate-binding protein, inducible antibody
    see all

Anti-PABPC4 antibody images

  • All lanes : Anti-PABPC4 antibody (ab66897) at 1.25 µg/ml

    Lane 1 : Molecular weight markers
    Lane 2 : HepG2 cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 71 kDa
    Observed band size : 71 kDa
    Additional bands at : 46 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling PABPC4 with ab66897 at 4-8µg/ml. Arrows indicate positively labelled epithelial cells of the renal tubule. Magnification: 400X.

References for Anti-PABPC4 antibody (ab66897)

ab66897 has not yet been referenced specifically in any publications.

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