Human Predicted to work with:
Recombinant fragment, corresponding to amino acids 20-155 of Human PACAP receptor (BC117116).
Human fetal heart lysate
Lyophilised:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.
Belongs to the G-protein coupled receptor 2 family.