Overview

  • Product nameAnti-PACAP receptor antibody
    See all PACAP receptor primary antibodies
  • Description
    Rabbit polyclonal to PACAP receptor
  • Tested applicationsSuitable for: IHC-P, ICC, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Synthetic peptide:

    LSKSSSQIRMSGLPADNLAT

    conjugated to KLH, corresponding to amino acids 506-525 of Human PACAP receptor.

Properties

Applications

Our Abpromise guarantee covers the use of ab28670 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500.
ICC 1/1000.
WB 1/1000. Detects a band of approximately 40-60 kDa (predicted molecular weight: 55 kDa).

Target

  • FunctionThis is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
  • Tissue specificityMost abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 2 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADCYAP1 R1 antibody
    • ADCYAP1R 1 antibody
    • ADCYAP1R1 antibody
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1 antibody
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I antibody
    • PAC 1 antibody
    • PAC1 antibody
    • PAC1R antibody
    • PACAP receptor 1 antibody
    • PACAP type I receptor antibody
    • PACAP-R-1 antibody
    • PACAP-R1 antibody
    • PACAP1 R antibody
    • PACAPR antibody
    • PACAPRI antibody
    • PACR_HUMAN antibody
    • Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop antibody
    • Pituitary adenylate cyclase activating polypeptide receptor antibody
    • Pituitary adenylate cyclase activating polypeptide type I receptor precursor antibody
    • Pituitary adenylate cyclase-activating polypeptide 1, receptor for antibody
    • Pituitary adenylate cyclase-activating polypeptide type I receptor antibody
    • pvr1 antibody
    see all

Anti-PACAP receptor antibody images

  • ab28670 staining Human PACAP receptor in human myenteric ganglia cells of the small intestine by immunohistochemistry using paraffin embedded tissue.

References for Anti-PACAP receptor antibody (ab28670)

This product has been referenced in:
  • Ortner A  et al. VPAC receptor mediated tumor cell targeting by protamine based nanoparticles. J Drug Target 18:457-67 (2010). ICC ; Human . Read more (PubMed: 20050817) »

See 1 Publication for this product

Product Wall

Application Western blot
Loading amount 25 µg
Gel Running Conditions Reduced Denaturing (10% Gel)
Sample Mouse Tissue lysate - whole (Dorsal Hippocampal Tissue)
Specification Dorsal Hippocampal Tissue
Blocking step I-Block as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 0.2% · Temperature: 20°C
Username

Abcam user community

Verified customer

Submitted Oct 14 2013

Thank you for your reply.

Because ab8901 has been validated for use in rat and RIA, it will be guaranteed for your experiments and would not qualify for the testing discount program. I would be happy to manually submit your Abreview and award...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"