Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab2532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 50,37 kDa (predicted molecular weight: 50 kDa).
ELISA 1/32000.

Target

  • Function
    May play a role in vesicle formation and transport.
  • Tissue specificity
    Highly expressed in brain and in a lesser extent in heart, pancreas and liver.
  • Sequence similarities
    Belongs to the PACSIN family.
    Contains 1 FCH domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).
  • Cellular localization
    Cytoplasm. Colocalizes with dynamin I at vesicular structures in the cell body and neurites.
  • Information by UniProt
  • Database links
  • Alternative names
    • A830061D09Rik antibody
    • Dynamin PRD-interacting protein antibody
    • Dynamin proline-rich domain-interacting protein antibody
    • H74 antibody
    • KIAA1379 antibody
    • MGC114042 antibody
    • MGC56324 antibody
    • mKIAA1379 antibody
    • OTTHUMP00000016231 antibody
    • PACN1_HUMAN antibody
    • Pacsin1 antibody
    • PASCIN antibody
    • Protein kinase C and casein kinase substrate in neurons 1 antibody
    • Protein kinase C and casein kinase substrate in neurons protein 1 antibody
    • SDPI antibody
    • Synaptic, dynamin-associated protein I antibody
    • Syndapin 1 antibody
    • Syndapin antibody
    • Syndapin-I antibody
    • zgc:114042 antibody
    • zgc:56324 antibody
    see all

Images

  • Anti-PACSIN1 antibody (ab2532) at 1 µg/ml + HUman Brain (hippocampus) lysate at 35 µg

    Predicted band size : 50 kDa
    Observed band size : 50 kDa
    Additional bands at : 37 kDa. We are unsure as to the identity of these extra bands.

References

ab2532 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab2532.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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