Anti-PAF-R antibody (ab104162)
Key features and details
- Rabbit polyclonal to PAF-R
- Suitable for: ICC, IP, WB, Flow Cyt
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PAF-R antibody -
Description
Rabbit polyclonal to PAF-R -
Host species
Rabbit -
Tested applications
Suitable for: ICC, IP, WB, Flow Cytmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Pig, Rhesus monkey -
Immunogen
Synthetic peptide corresponding to Human PAF-R aa 1-100 (N terminal) conjugated to keyhole limpet haemocyanin.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.05% BSA, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab104162 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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WB |
1/200. Predicted molecular weight: 39 kDa.
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Flow Cyt |
Use at an assay dependent concentration.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
Notes |
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ICC
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
WB
1/200. Predicted molecular weight: 39 kDa. |
Flow Cyt
Use at an assay dependent concentration. ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
Target
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Function
Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. -
Tissue specificity
Expressed in the placenta, lung, left and right heart ventricles, heart atrium, leukocytes and differentiated HL-60 granulocytes. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 5724 Human
- Entrez Gene: 19204 Mouse
- Entrez Gene: 58949 Rat
- Omim: 173393 Human
- SwissProt: P25105 Human
- SwissProt: Q62035 Mouse
- SwissProt: Q9XSD4 Pig
- SwissProt: P46002 Rat
see all -
Alternative names
- OTTHUMP00000004041 antibody
- OTTMUSP00000010350 antibody
- PAF R antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (9)
ab104162 has been referenced in 9 publications.
- Yang J et al. Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke. Cell Death Dis 12:23 (2021). PubMed: 33414461
- Sudaryatma PE et al. Bovine Respiratory Syncytial Virus Enhances the Adherence of Pasteurella multocida to Bovine Lower Respiratory Tract Epithelial Cells by Upregulating the Platelet-Activating Factor Receptor. Front Microbiol 11:1676 (2020). PubMed: 32849350
- Bhalla M et al. A1 adenosine receptor signaling reduces Streptococcus pneumoniae adherence to pulmonary epithelial cells by targeting expression of platelet-activating factor receptor. Cell Microbiol 22:e13141 (2020). PubMed: 31709673
- Liu G et al. Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome. Mucosal Immunol 12:862-873 (2019). PubMed: 30976089
- Liang H et al. LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d. Theranostics 8:1180-1194 (2018). PubMed: 29464008
- Patel PS & Kearney JF CD36 and Platelet-Activating Factor Receptor Promote House Dust Mite Allergy Development. J Immunol 199:1184-1195 (2017). PubMed: 28667161
- Vimalanathan S et al. Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells. Virus Res 233:51-59 (2017). ICC ; Human . PubMed: 28279802
- Yu Y et al. The expression of platelet-activating factor receptor modulates the cisplatin sensitivity of ovarian cancer cells: a novel target for combination therapy. Br J Cancer N/A:N/A (2014). WB . PubMed: 24921917
- Yuan D et al. Enhanced permeability responses to inflammation in streptozotocin-induced diabetic rat venules: Rho-mediated alterations of actin cytoskeleton and VE-cadherin. Am J Physiol Heart Circ Physiol 307:H44-53 (2014). PubMed: 24778164